Harnessing synthetic biology to engineer organoids and tissues
The development of an organism depends on intrinsic genetic programs of progenitor cells
and their spatiotemporally complex extrinsic environment. Ex vivo generation of organoids …
and their spatiotemporally complex extrinsic environment. Ex vivo generation of organoids …
Programmable interactions with biomimetic DNA linkers at fluid membranes and interfaces
BM Mognetti, P Cicuta… - Reports on progress in …, 2019 - iopscience.iop.org
At the heart of the structured architecture and complex dynamics of biological systems are
specific and timely interactions operated by biomolecules. In many instances, biomolecular …
specific and timely interactions operated by biomolecules. In many instances, biomolecular …
A quantitative assessment of the dynamic modification of lipid–DNA probes on live cell membranes
Synthetic lipid–DNA probes have recently attracted much attention for cell membrane
analysis, transmembrane signal transduction, and regulating intercellular networks. These …
analysis, transmembrane signal transduction, and regulating intercellular networks. These …
DNA nanostructures for exploring cell–cell communication
Y Wang, Y Xiong, K Shi, CY Effah, L Song… - Chemical Society …, 2024 - pubs.rsc.org
The process of coordinating between the same or multiple types of cells to jointly execute
various instructions in a controlled and carefully regulated environment is a very appealing …
various instructions in a controlled and carefully regulated environment is a very appealing …
Design principles for pluripotent stem cell‐derived organoid engineering
Human morphogenesis is a complex process involving distinct microenvironmental and
physical signals that are manipulated in space and time to give rise to complex tissues and …
physical signals that are manipulated in space and time to give rise to complex tissues and …
Programming the self-organization of endothelial cells into perfusable microvasculature
The construction of three-dimensional (3D) microvascular networks with defined structures
remains challenging. Emerging bioprinting strategies provide a means of patterning …
remains challenging. Emerging bioprinting strategies provide a means of patterning …
Controlling Cell Interactions with DNA Directed Assembly
The creation of complex cellular environments is critical to mimicking tissue environments
that will play a critical role in next‐generation tissue engineering, stem cell programming …
that will play a critical role in next‐generation tissue engineering, stem cell programming …
DNA hybridization to control cellular interactions
A key challenge in many biological studies is the inability to control the placement of cells in
two and three dimensions. As our understanding of the importance of complexity in cellular …
two and three dimensions. As our understanding of the importance of complexity in cellular …
Lipid-DNA conjugates for cell membrane modification, analysis, and regulation
Lipids and DNAs are two major building blocks of life. Interestingly, by chemically linking
these two natural compounds together, synthetic lipid-DNA conjugates exhibit several …
these two natural compounds together, synthetic lipid-DNA conjugates exhibit several …
[HTML][HTML] Simple, affordable, and modular patterning of cells using DNA
KA Cabral, DM Patterson, OJ Scheideler… - Journal of visualized …, 2021 - ncbi.nlm.nih.gov
The relative positioning of cells is a key feature of the microenvironment that organizes cell-
cell interactions. To study the interactions between cells of the same or different type …
cell interactions. To study the interactions between cells of the same or different type …