Human parturition at term and preterm is an inflammatory process synchronously executed
by both fetomaternal tissues to transition them from a quiescent state t an active state of …

Objectives: To improve preclinical drug testing during pregnancy, we developed multiple
microfluidic organ-on-chip (OOC) devices that represent the structure, functions, and …

Introduction The placenta is essential for fetal growth and survival and maintaining a
successful pregnancy. The sterility of the placenta has been challenged recently; however …

Genital mycoplasmas can break the cervical barrier and cause intraamniotic infection and
preterm birth. This study developed a six-chamber vagina-cervix-decidua-organ-on-a-chip …

This study determined if exosomes from ectocervical epithelial (ECTO) cells infected with
Ureaplasma parvum (U. parvum) can carry bacterial antigens and cause inflammation at the …

During human pregnancy the chorion (fetal) lines decidua (maternal) creating the feto
maternal interface. Despite their proximity, resident decidual immune cells remain quiescent …

Background Environmental exposure to toxicants is a major risk factor for spontaneous
preterm birth (PTB,< 37 weeks). Toxicants and drugs administered to patients are …

Oxidative stress (OS) and inflammation arising from cellular derangements at the fetal
membrane‐decidual interface (feto‐maternal interface [FMi]) is a major antecedent to …

The process of human parturition involves inflammation at the interface where fetal chorion
trophoblast cells interact with maternal decidual stromal (DS) cells and maternal immune …

Preterm, prelabor rupture of the human fetal membranes (pPROM) is involved in 40% of
spontaneous preterm births worldwide. Cellular-level disturbances and inflammation are …