Sleep is critical for diverse aspects of brain function in animals ranging from invertebrates to
humans. Powerful genetic tools in the fruit fly Drosophila melanogaster have identified—at …

The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

In the last three decades the two‐process model of sleep regulation has served as a major
conceptual framework in sleep research. It has been applied widely in studies on fatigue …

Sleep is homeostatically regulated with sleep pressure accumulating with the increasing
duration of prior wakefulness. Yet, a clear understanding of the molecular components of the …

The dynamic nature of sleep in many animals suggests distinct stages that serve different
functions. Genetic sleep induction methods in animal models provide a powerful way to …

Sleep is a dynamic process comprising multiple stages, each associated with distinct
electrophysiological properties and potentially serving different functions. While these …

Genome-wide association studies (GWAS) in humans have identified loci robustly
associated with several heritable diseases or traits, yet little is known about the functional …

The recent development of automatised methods to score various behaviours on a large
number of animals provides biologists with an unprecedented set of tools to decipher these …

During sleep, most animal species enter a state of reduced consciousness characterized by
a marked sensory disconnect. Yet some processing of the external world must remain intact …

Food consumption is thought to induce sleepiness. However, little is known about how
postprandial sleep is regulated. Here, we simultaneously measured sleep and food intake of …