During vertebrate development, a wide variety of cell types and tissues emerge from a single
fertilized oocyte. One of these tissues, the central nervous system, contains many types of …

Multipotent neural progenitor cells (NPCs) undergo self-renewal while producing neurons,
astrocytes, and oligodendrocytes. These processes are controlled by multiple basic helix …

The pace of human brain development is highly protracted compared with most other
species,,,,,–. The maturation of cortical neurons is particularly slow, taking months to years to …

RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

Active maintenance of genome stability is a prerequisite for the development and function of
the nervous system. The high replication index during neurogenesis and the long life of …

During brain development, neural stem cells change their competency to give sequential
rise to neurons and glial cells. Expression of the basic helix-loop-helix (bHLH)-type cell-fate …

The size of the cerebral cortex increases dramatically across amniotes, from reptiles to great
apes. This is primarily due to different numbers of neurons and glial cells produced during …

High Mobility Group Box (HMGB) proteins are small architectural DNA binding proteins that
regulate multiple genomic processes such as DNA damage repair, nucleosome sliding …

HMGA (high mobility group A)(HMGA1 and HMGA2) are small non-histone proteins that can
bind DNA and modify chromatin state, thus modulating the accessibility of regulatory factors …

High mobility group (HMG) proteins are the most abundant non-histone chromatin
associated proteins. HMG proteins bind to DNA and nucleosome and alter the structure of …