Thoracic aortic aneurysm (TAA) develops silently and asymptomatically and is a major
cause of mortality. TAA prevalence is greatly underestimated, it is usually diagnosed …

Altered proteoglycan (PG) and glycosaminoglycan (GAG) distribution within the aortic wall
has been implicated in thoracic aortic aneurysm and dissection (TAAD). This review was …

Aortic rupture and dissection are life-threatening complications of ascending thoracic aortic
aneurysms (aTAAs), and risk assessment has been largely based on the monitoring of …

Background A bicuspid aortic valve (BAV) is the most common congenital cardiac
malformation and is associated with ascending aortic dilation in 60%–80% of patients. In this …

Objective Our basic understanding of ascending thoracic aortic aneurysm (ATAA)
pathogenesis is still very limited, hampering early diagnosis, risk prediction, and …

Thoracic aortic aneurysm (TAA) represents a major cause of mortality and morbidity in
Western countries. The natural history of TAA is indolent, with patients usually being …

This study focuses on recent advances in proteomics and provides an up-to-date use of this
technology in identifying cardiovascular disease (CVD) biomarkers. A total of eight …

OBJECTIVES We aimed to evaluate the impact of microRNAs to predict the bicuspid aortic
valve (BAV)-associated aortopathy. METHODS Sixty-three BAV patients (mean age 47±11 …

Aims Understanding the mechanisms underlying ascending aortic dilation is imperative for
refined risk stratification of these patients, particularly among incidentally identified patients …

Abdominal aortic aneurysms (AAA), are usually asymptomatic until rupture causes fatal
bleeding, posing a major vascular health problem. AAAs are associated with advanced age …