The environmental and health impacts of steroids and hormones in wastewater effluent, as well as existing removal technologies: a review

MMS Yazdan, R Kumar, SW Leung - Ecologies, 2022 - mdpi.com
Micro-pollutants especially estrogens, progesterone, androgens, glucocorticoids, and
growth hormones, are biological and chemical impurities that find their way into natural …

Steroids in teleost fishes: A functional point of view

J Tokarz, G Möller, MH de Angelis, J Adamski - Steroids, 2015 - Elsevier
Steroid hormones are involved in the regulation of a variety of processes like embryonic
development, sex differentiation, metabolism, immune responses, circadian rhythms, stress …

Synthetic progestins in waste and surface waters: Concentrations, impacts and ecological risk

MJ Rocha, E Rocha - Toxics, 2022 - mdpi.com
Synthetic progestins (PGs) are a large family of hormones used in continuously growing
amounts in human and animal contraception and medicinal therapies. Because wastewater …

Levonorgestrel causes feminization and dose-dependent masculinization in medaka fish (Oryzias latipes): Endocrine-disruption activity and its correlation with sex …

A Watanabe, T Myosho, A Ishibashi… - Science of the Total …, 2023 - Elsevier
The effect of a synthetic progestin, levonorgestrel (LNG), on the sex of exposed embryos
was examined in medaka fish (Oryzias latipes). The aims of this study are to clarify the dual …

Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation

W Xie, X Ge, L Li, A Yao, X Wang, M Li, X Gong, Z Chu… - Molecular autism, 2018 - Springer
Background Recent literatures indicate that maternal hormone exposure is a risk factor for
autism spectrum disorder (ASD). We hypothesize that prenatal progestin exposure may …

The progestin levonorgestrel affects sex differentiation in zebrafish at environmentally relevant concentrations

J Hua, J Han, Y Guo, B Zhou - Aquatic Toxicology, 2015 - Elsevier
Synthetic progestins have become widespread environmental contaminants and may cause
adverse effects on fish. In the present study, we investigated the effects of levonorgestrel …

Prenatal progestin exposure is associated with autism spectrum disorders

L Li, M Li, J Lu, X Ge, W Xie, Z Wang, X Li, C Li… - Frontiers in …, 2018 - frontiersin.org
We have previously reported that prenatal progestin exposure induces autism-like behavior
in offspring through ERβ (estrogen receptor β) suppression in the brain, indicating that …

The binary mixtures of megestrol acetate and 17α-ethynylestradiol adversely affect zebrafish reproduction

J Hua, J Han, X Wang, Y Guo, B Zhou - Environmental Pollution, 2016 - Elsevier
Synthetic progesterones and estrogens are broadly used bioactive pharmaceutical agents
and have been detected in aquatic environments. In the present study, we investigated the …

The other side of progestins: effects in the brain

S Giatti, RC Melcangi… - Journal of Molecular …, 2016 - jme.bioscientifica.com
Progestins are a broad class of progestational agents widely differing in their chemical
structures and pharmacological properties. Despite emerging data suggest that progestins …

The effects of norethindrone on the ontogeny of gene expression along the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes in zebrafish …

Y Luo, H Chen, D Li, M Zhan, L Hou, W Dong… - Science of the Total …, 2020 - Elsevier
Little is known about the molecular effects of progestins on the hypothalamic-pituitary-
adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes in fish prior to sexual …