Pharmacological activity of capsaicin: Mechanisms and controversies

W Zhang, Y Zhang, J Fan… - Molecular Medicine …, 2024 - spandidos-publications.com
Capsaicin, which is abundant in chili peppers, exerts antioxidative, antitumor, antiulcer and
analgesic effects and it has demonstrated potential as a treatment for cardiovascular …

Diet and lifestyle impact the development and progression of Alzheimer's dementia

S Arora, JA Santiago, M Bernstein… - Frontiers in Nutrition, 2023 - frontiersin.org
Dementia is a growing public health concern, with an estimated prevalence of 57 million
adults worldwide. Alzheimer's disease (AD) accounts for 60–80% of the cases. Clinical trials …

Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain?

JL Silva, EA Santos, JI Alvarez-Leite - Nutrients, 2023 - mdpi.com
Capsaicin, a lipophilic, volatile compound, is responsible for the pungent properties of chili
peppers. In recent years, a significant increase in investigations into its properties has …

Ameliorative role of bioactive phytoconstituents targeting obesity associated NAFLD by modulation of inflammation and lipogenesis pathways: a comprehensive …

PA Barbhuiya, S Sen, MP Pathak - Phytochemistry Reviews, 2024 - Springer
By 2025, the projected global obesity rates for both men and women are 18% and 21%,
respectively. Obesity raises the risk of several comorbidities like cardiovascular disease …

Nanoparticles as new elicitors for the production of bioactive and phytochemicals in vitro and in vivo plant culture

M Darbahani, MR Ghiyasi, M Rahaie - Phytochemistry Reviews, 2024 - Springer
Plants have been used for their beneficial compounds especially therapeutic and medicinal
properties over the centuries. Various applications of plants in industry and medicine are …

[HTML][HTML] Moderate capsaicin-containing kochujang alleviates memory impairment through the gut-brain axis in rats with scopolamine-induced amnesia

MS Ryu, Y Yue, C Li, HJ Yang, T Zhang, X Wu… - Biomedicine & …, 2024 - Elsevier
This study investigated the efficacy and mechanism of traditionally made kochujang (TMK)
with different capsaicin levels to alleviate memory impairment in rats with scopolamine …

Regulation Mechanism and Potential Value of Active Substances in Spices in Alcohol–Liver–Intestine Axis Health

J Huang, T Huang, J Li - International Journal of Molecular Sciences, 2024 - mdpi.com
Excessive alcohol intake will aggravate the health risk between the liver and intestine and
affect the multi-directional information exchange of metabolites between host cells and …

Hyperthyroidism, hypothyroidism, thyroid stimulating hormone, and dementia risk: results from the NHANES 2011–2012 and Mendelian randomization analysis

X Sheng, J Gao, K Chen, X Zhu… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction As the world ages, dementia places a heavy burden on society and the
economy, but current methods of diagnosing dementia are still limited and there are no …

[HTML][HTML] Capsaicin Reduces Obesity by Reducing Chronic Low-Grade Inflammation

J Yang, W Li, Y Wang - International Journal of Molecular Sciences, 2024 - mdpi.com
Chronic low-grade inflammation (CLGI) is associated with obesity and is one of its
pathogenetic mechanisms. Lipopolysaccharide (LPS), a component of Gram-negative …

Biomarkers and Novel Therapies of Diabetic Neuropathy: An Updated Review

N Aziz, SV Nehere, R Sinha, R Satyarthy… - Current …, 2024 - benthamdirect.com
Diabetic neuropathy is a persistent consequence of the biochemical condition known as
diabetes mellitus. As of now, the identification and management of diabetic neuropathy …