Fundamental Aspects of Phase-Separated Biomolecular Condensates
Biomolecular condensates, formed through phase separation, are upending our
understanding in much of molecular, cell, and developmental biology. There is an urgent …
understanding in much of molecular, cell, and developmental biology. There is an urgent …
[HTML][HTML] Coronin 2B deficiency induces nucleolar stress and neuronal apoptosis
H Wu, Y Yang, W Yi, Y Qiu, S Ma, J Xu, Y Fan… - Cell Death & …, 2024 - nature.com
In eukaryotes, the nucleolus is the critical non-membranous organelle within nuclei that is
responsible for ribosomal DNA (rDNA) transcription and ribosome biogenesis. The …
responsible for ribosomal DNA (rDNA) transcription and ribosome biogenesis. The …
Effects of Associative Interactions on the Phase Behavior of Complex Coacervates
ZM Jedlinska, RA Riggleman - Macromolecules, 2024 - ACS Publications
Associative polymer networks have shown major promise in the fabrication of self-healing
and responsive materials. They can also serve as simple models to study more complex …
and responsive materials. They can also serve as simple models to study more complex …
Exploring liquid-liquid phase separation in the organisation of Golgi matrix proteins
The Golgi apparatus is a critical organelle in protein sorting and lipid metabolism.
Characterized by its stacked, flattened cisternal structure, the Golgi exhibits distinct polarity …
Characterized by its stacked, flattened cisternal structure, the Golgi exhibits distinct polarity …
Spectrin condensates provide a nidus for assembling the periodic axonal structure
NP Boyer, R Sharma, T Wiesner, A Delamare… - bioRxiv, 2024 - biorxiv.org
Coordinated assembly of individual components into higher-order structures is a defining
theme in biology, but underlying principles are not well-understood. In neurons, alpha/beta …
theme in biology, but underlying principles are not well-understood. In neurons, alpha/beta …
Bacterial cell cycle regulator MatP forms biomolecular condensates and directly interacts with cell division protein FtsZ
I Barros-Medina, MA Robles-Ramos… - bioRxiv, 2024 - biorxiv.org
Bacterial cytokinesis is driven by a contractile ring of FtsZ protein polymers at midcell. FtsZ
can also form phase-separated biomolecular condensates with potential implications for …
can also form phase-separated biomolecular condensates with potential implications for …