Cholestatic and non-alcoholic fatty liver disease (NAFLD) share several key
pathophysiological mechanisms which can be targeted by novel therapeutic concepts that …

South Asians (from Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri
Lanka) make up one quarter of the world's population and are one of the fastest-growing …

Background: Diabetic retinopathy is a leading cause of visual impairment in working-age
adults worldwide. Duration of diabetes is a major risk factor associated with the development …

Background Laser treatment for diabetic retinopathy is often associated with visual field
reduction and other ocular side-effects. Our aim was to assess whether long-term lipid …

Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription
factor that belongs to the steroid hormone receptor superfamily. PPARα is expressed …

Statins are highly effective drugs prescribed to millions of people to lower LDL-cholesterol
and decrease cardiovascular risk. The benefits of statin therapy seen in randomized clinical …

Despite best evidence-based treatment including statins, residual cardiovascular risk poses
a major challenge for clinicians in the twenty first century. Atherogenic dyslipidaemia, in …

The triglyceride–glucose (TyG) index has been correlated with insulin resistance. We aim to
investigate the role of the TyG index on cardiovascular (CV) events in type 2 diabetes …

Dyslipidemia is defined by abnormal levels of plasma lipoproteins. Several different types of
dyslipidemia can be distinguished. An important group of drugs used in the treatment of …

Recent data suggest that the assembly of very low density lipoprotein is fundamentally
altered in type 2 diabetes, explaining the overproduction of large type 1 very low density …