Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …

Neurogenic hypertension is associated with excessive sympathetic nerve activity to the
kidneys and portions of the cardiovascular system. Here we examine the brain regions that …

Background: Aberrant sympathetic nerve activity exacerbates cardiovascular risk in
hypertension and diabetes, which are common comorbidities, yet clinically sympathetic …

Twenty‐five years ago, a new physiological preparation called the working heart–brainstem
preparation (WHBP) was introduced with the claim it would provide a new platform allowing …

The neurons secreting oxytocin (OXY) and vasopressin (AVP) are located mainly in the
supraoptic, paraventricular, and suprachiasmatic nucleus of the brain. Oxytocinergic and …

The purpose of this study was to determine whether there are sex differences in the
cardiorespiratory and sympathetic neurocirculatory responses to central, peripheral, and …

Acute oxygen (O2) sensing is essential for adaptation of organisms to hypoxic environments
or medical conditions with restricted exchange of gases in the lung. The main acute O2 …

Recent evidence has suggested that the carotid bodies might act as immunological sensors,
detecting pro-inflammatory mediators and signalling to the central nervous system, which, in …

Substantial advances have been made recently into the discovery of fundamental
mechanisms underlying the neural control of breathing and even some inroads into …