Pancreatic β-cells are finely tuned to secrete insulin so that plasma glucose levels are
maintained within a narrow physiological range (3.5-5.5 mmol/L). Hyperinsulinaemic …

Congenital hyperinsulinism (CHI) is a condition characterised by severe and recurrent
hypoglycaemia in infants and young children caused by inappropriate insulin over …

Hyperinsulinemic hypoglycemia (HH) is characterized by unregulated insulin release,
leading to persistently low blood glucose concentrations with lack of alternative fuels, which …

Background: Hyperinsulinism (HI) due to dysregulation of pancreatic beta-cell insulin
secretion is the most common and most severe cause of persistent hypoglycemia in infants …

Hypoglycemia is the result of defects/impairment in glucose homeostasis. The main
etiological causes are metabolic and/or endocrine and/or other congenital disorders …

Congenital hyperinsulinism (CHI) is a rare disease characterized by an unregulated insulin
release, leading to hypoglycaemia. It is the most frequent cause of persistent and severe …

Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycmia in
neonatles and children. The inappropriate secretion of insulin by the pancreatic β-cells …

Abstract Background/Aims: Congenital hyperinsulinism (CHI) is a rare disease characterized
by recurrent severe hypoglycemia. In the diffuse form of CHI, pharmacotherapy is the …

Hyperinsulinaemic hypoglycaemia (HH) is a biochemical finding of low blood glucose levels
due to the dysregulation of insulin secretion from pancreatic β-cells. Under normal …

Hyperinsulinaemic hypoglycaemia (HH) is the most common cause of persistent
hypoglycaemia in infants and children with incidence estimated at 1 per 50,000 live births …