Autonomic control of cerebral blood flow: fundamental comparisons between peripheral and cerebrovascular circulations in humans

JL Koep, CE Taylor, JS Coombes… - The Journal of …, 2022 - Wiley Online Library
Understanding the contribution of the autonomic nervous system to cerebral blood flow
(CBF) control is challenging, and interpretations are unclear. The identification of calcium …

High-intensity interval exercise and cerebrovascular health: curiosity, cause, and consequence

SJE Lucas, JD Cotter, P Brassard… - Journal of Cerebral …, 2015 - journals.sagepub.com
Exercise is a uniquely effective and pluripotent medicine against several noncommunicable
diseases of westernised lifestyles, including protection against neurodegenerative …

Association of intensive vs standard blood pressure control with regional changes in cerebral small vessel disease biomarkers: post hoc secondary analysis of the …

T Rashid, K Li, JB Toledo, I Nasrallah… - JAMA network …, 2023 - jamanetwork.com
Importance Little is known about the associations of strict blood pressure (BP) control with
microstructural changes in small vessel disease markers. Objective To investigate the …

Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist …

AA Phillips, DER Warburton… - Journal of Cerebral …, 2014 - journals.sagepub.com
Individuals with high-level spinal cord injury (SCI) experience low blood pressure (BP) and
cognitive impairments. Such dysfunction may be mediated in part by impaired neurovascular …

[HTML][HTML] Why is the neural control of cerebral autoregulation so controversial?

PN Ainslie, P Brassard - F1000prime reports, 2014 - ncbi.nlm.nih.gov
Cerebral autoregulation refers to the mechanisms that act to keep cerebral blood flow (CBF)
constant during changes in blood pressure. The mechanisms of cerebral autoregulation …

Sympathetic control of the brain circulation: appreciating the complexities to better understand the controversy

P Brassard, MM Tymko, PN Ainslie - Autonomic Neuroscience, 2017 - Elsevier
Although the human cerebral circulation is richly innervated with sympathetic nerve fibers,
the role of sympathetic nerve activity (SNA) on the regulation of cerebral blood flow (CBF) …

Intracranial mechanisms for preserving brain blood flow in health and disease

FD McBryde, SC Malpas, JFR Paton - Acta physiologica, 2017 - Wiley Online Library
The brain is an exceptionally energetically demanding organ with little metabolic reserve,
and multiple systems operate to protect and preserve the brain blood supply. But how does …

Blood flow distribution during heat stress: cerebral and systemic blood flow

S Ogoh, K Sato, K Okazaki… - Journal of Cerebral …, 2013 - journals.sagepub.com
The purpose of the present study was to assess the effect of heat stress-induced changes in
systemic circulation on intra-and extracranial blood flows and its distribution. Twelve healthy …

Cerebrovascular reactivity and cerebral autoregulation are improved in the supine posture compared to upright in healthy men and women

ME Favre, V Lim, MJ Falvo, JM Serrador - PloS one, 2020 - journals.plos.org
Cerebrovascular reactivity and cerebral autoregulation are two major mechanisms that
regulate cerebral blood flow. Both mechanisms are typically assessed in either supine or …

Impact of transient hypotension on regional cerebral blood flow in humans

NCS Lewis, KJ Smith, AR Bain, KW Wildfong… - Clinical …, 2015 - portlandpress.com
We examined the impact of progressive hypotension with and without hypocapnia on
regional extracranial cerebral blood flow (CBF) and intracranial velocities. Participants …