[HTML][HTML] Neisseria gonorrhoeae host adaptation and pathogenesis

SJ Quillin, HS Seifert - Nature Reviews Microbiology, 2018 - nature.com
The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

The role of TLR2 in infection and immunity

L Oliveira-Nascimento, P Massari… - Frontiers in …, 2012 - frontiersin.org
Toll-like receptors (TLRs) are recognition molecules for multiple pathogens, including
bacteria, viruses, fungi, and parasites. TLR2 forms heterodimers with TLR1 and TLR6, which …

Pathogen recognition and inflammatory signaling in innate immune defenses

TH Mogensen - Clinical microbiology reviews, 2009 - Am Soc Microbiol
The innate immune system constitutes the first line of defense against invading microbial
pathogens and relies on a large family of pattern recognition receptors (PRRs), which detect …

Toll-like receptor signalling

S Akira, K Takeda - Nature reviews immunology, 2004 - nature.com
One of the mechanisms by which the innate immune system senses the invasion of
pathogenic microorganisms is through the Toll-like receptors (TLRs), which recognize …

Toll-like receptors

K Takeda, T Kaisho, S Akira - Annual review of immunology, 2003 - annualreviews.org
The innate immune system in drosophila and mammals senses the invasion of
microorganisms using the family of Toll receptors, stimulation of which initiates a range of …

Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

EA Leadbetter, IR Rifkin, AM Hohlbaum, BC Beaudette… - Nature, 2002 - nature.com
Autoreactive B cells are present in the lymphoid tissues of healthy individuals, but typically
remain quiescent. When this homeostasis is perturbed, the formation of self-reactive …

Recognition of pathogen-associated molecular patterns by TLR family

S Akira, H Hemmi - Immunology letters, 2003 - Elsevier
Toll-like receptors (TLRs) are type I transmembrane proteins involved in innate immunity by
recognizing microbial conserved structures. Recent studies have shown that TLR3 …

Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

ES Van Amersfoort, TJC Van Berkel… - Clinical microbiology …, 2003 - Am Soc Microbiol
Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

Recognition and signaling by toll-like receptors

AP West, AA Koblansky, S Ghosh - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
Toll-like receptors (TLRs) are transmembrane proteins that detect invading pathogens by
binding conserved, microbially derived molecules and that induce signaling cascades for …

Host-response patterns of intramammary infections in dairy cows

YH Schukken, J Günther, J Fitzpatrick… - Veterinary immunology …, 2011 - Elsevier
Many different bacterial species have the ability to cause an infection of the bovine
mammary gland and the host response to these infections is what we recognize as mastitis …