Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

Radiotherapy should have low toxicity in the entrance channel (normal tissue) and be very
effective in cell killing in the target region (tumour). In this regard, ions heavier than protons …

Technology has a pivotal role in the continuous development of radiotherapy. The long road
toward modern 'high‐tech'radiation oncology has been studded with discoveries and …

Purpose To establish a beam monitoring and dosimetry system to enable the FLASH dose
rate carbon ion irradiation and investigate, at different oxygen concentrations, the in vitro …

The efficacy of radiation therapy (RT) is often limited by the poor response of hypoxia inside
most solid tumors. The development of a theranostic nanoplatform for precision‐imaging …

Background and Significance The application of heavy ion beams in cancer therapy must
account for the increasing relative biological effectiveness (RBE) with increasing penetration …

This review presents the author's view on modern trends in the development of charged
particle accelerators for various applications, which is based on his own experience in this …

Simple Summary Carbon-ion radiotherapy is a potential elective treatment option for hypoxic
tumors. Its high linear energy transfer enables enhanced cell killing in radiation-resistant …

The radiosensitivity of biological systems is strongly affected by the system oxygenation. On
the nanoscopic scale and molecular level, this effect is considered to be strongly related to …

Applied nuclear physics is an essential part of the research activity at many particle
accelerators. New, large accelerator facilities are currently under construction in Europe …