RASSF1A tumour suppressor: Target the network for effective cancer therapy
The RASSF1A tumour suppressor is a scaffold protein that is involved in cell signalling.
Increasing evidence shows that this protein sits at the crossroad of a complex signalling …
Increasing evidence shows that this protein sits at the crossroad of a complex signalling …
MGMT-methylation in non-neoplastic diseases of the central nervous system
S Teuber-Hanselmann, K Worm, N Macha… - International journal of …, 2021 - mdpi.com
Quantifying O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation plays
an essential role in assessing the potential efficacy of alkylating agents in the chemotherapy …
an essential role in assessing the potential efficacy of alkylating agents in the chemotherapy …
Disulfiram ameliorates bleomycin induced pulmonary inflammation and fibrosis in rats
N Hamidi, F Feizi, A Azadmehr, E Zabihi… - Biotechnic & …, 2023 - Taylor & Francis
Bleomycin (BL) is a widely used anticancer drug that can cause pulmonary fibrosis due to
increased fibroblast proliferation and increased secretion of extracellular matrix. RASSF1A …
increased fibroblast proliferation and increased secretion of extracellular matrix. RASSF1A …
RASSF1A and p16 promoter methylation and treatment response in chronic hepatitis C genotype 1b patients treated with pegylated interferon/ribavirin
NS Kokanov, MM Krajnović… - Archives of Biological …, 2022 - doiserbia.nb.rs
Prevention of chronic hepatitis C (CHC) and its complications is based on antiviral therapy
and early detection of reliable molecular markers in persons under risk. We investigated …
and early detection of reliable molecular markers in persons under risk. We investigated …
Diagnostic performance of RASSF1A and CDKN2A gene methylation versus a-fetoprotein in hepatocellular carcinoma
H Nomeir, HG El-Sheredy, A Nomeir… - Clinical and …, 2022 - termedia.pl
Results The tumor group was significantly more methylated in both genes than the cirrhosis
and the control groups. The RASSF1A gene was highly methylated in advanced tumor …
and the control groups. The RASSF1A gene was highly methylated in advanced tumor …
Hepatitis C: Host and viral factors associated with response to therapy and progression of liver fibrosis
S Jovanovic-Cupic, A Bozovic… - Hepatitis C: From …, 2018 - books.google.com
The goal of this study was to identify the baseline host and viral factors of response to
antiviral therapy in patients with chronic hepatitis C. Compared with interferon/ribavirin …
antiviral therapy in patients with chronic hepatitis C. Compared with interferon/ribavirin …
Variability of the HCV core region and host genetic and epigenetic factors can predict the response to pegylated interferon/ribavirin therapy in genotype 1b hepatitis C …
N Kokanov, S Jovanović-Ćupić, M Šiljić… - Archives of Biological …, 2023 - vinar.vin.bg.ac.rs
Variations in the hepatitis C virus (HCV) core sequence have been related to disease
progression and response to antiviral therapy. Previously we showed that the methylation …
progression and response to antiviral therapy. Previously we showed that the methylation …
Establishing a research production line in real-life settings: the case of Hepatitis C management in a viral hepatitis specialized Egyptian center
M El Kassas, M Eltabbakh, M Elbadry… - Current Medical …, 2022 - Taylor & Francis
Efforts toward eradicating the Hepatitis C virus (HCV) have advanced rapidly, due to the
development of direct-acting antivirals (DAAs), especially with the appearance of pan …
development of direct-acting antivirals (DAAs), especially with the appearance of pan …
[HTML][HTML] Influence of some methylated hepatocarcinogenesis-related genes on the response to antiviral therapy and development of fibrosis in chronic hepatitis C …
WSEM Mostafa, MHS Al-Dahr, DAH Omran… - Clinical and …, 2020 - ncbi.nlm.nih.gov
Methods A total of 159 chronic hepatitis Egyptian patients versus 100 healthy control group
were included. The methylation profile of a panel 9 genes (SFRP1, p14, p73, APC, DAPK …
were included. The methylation profile of a panel 9 genes (SFRP1, p14, p73, APC, DAPK …
The Molecular Background Associated with the Progression of Hepatitis C to Hepatocellular Carcinoma
ARN Zekri, AA Bahnassy… - Hepatitis C-From …, 2018 - books.google.com
Hepatocellular carcinoma (HCC) is a major health problem worldwide. The DNA PM of
cancer-related genes plays an important role in the development and progression of HCC …
cancer-related genes plays an important role in the development and progression of HCC …