PD-1/PD-L1 based combinational cancer therapy: icing on the cake

J Zhang, Y Yan, J Li, R Adhikari, L Fu - Frontiers in Pharmacology, 2020 - frontiersin.org
Cancer has been a major global health problem due to its high morbidity and mortality.
While many chemotherapy agents have been studied and applied in clinical trials or in …

Cost effectiveness of immune checkpoint inhibitors for treatment of non-small cell lung cancer: a systematic review

H Ding, W Xin, Y Tong, J Sun, G Xu, Z Ye, Y Rao - PLoS One, 2020 - journals.plos.org
Background Immune checkpoint inhibitors (ICIs) for treatment of non-small cell lung cancer
(NSCLC) have been rapidly evolving. ICIs are likely to be more effective but also lead to …

First‐line atezolizumab in addition to bevacizumab plus chemotherapy for metastatic, nonsquamous non–small cell lung cancer: A United States–based cost …

XM Wan, X Luo, CQ Tan, XH Zeng, YC Zhang… - Cancer, 2019 - Wiley Online Library
Background The IMpower150 trial found that adding atezolizumab to the combination of
bevacizumab and chemotherapy improved survival for patients with metastatic …

Cost-effectiveness analysis of durvalumab plus chemotherapy in the first-line treatment of extensive-stage small cell lung cancer

D Ding, H Hu, S Li, Y Zhu, Y Shi, M Liao, J Liu… - Journal of the National …, 2021 - jnccn.org
Background: In the CASPIAN trial, durvalumab 1 chemotherapy demonstrated significant
improvements in overall survival compared with chemotherapy alone in patients with …

Cost-effectiveness of pembrolizumab in combination with chemotherapy versus chemotherapy and pembrolizumab monotherapy in the first-line treatment of …

RP Insinga, DJ Vanness, JL Feliciano… - … medical research and …, 2019 - Taylor & Francis
Objective: To describe the cost-effectiveness of pembrolizumab plus chemotherapy
(carboplatin and paclitaxel or nab-paclitaxel; P+ C) in metastatic, squamous, non-small-cell …

Cost–effectiveness of pembrolizumab versus chemotherapy as first-line treatment in PD-L1-positive advanced non-small-cell lung cancer in the USA

M Huang, GL Lopes, RP Insinga, T Burke… - …, 2019 - Taylor & Francis
Aim: This analysis aimed to evaluate the cost–effectiveness of pembrolizumab monotherapy
as first-line treatment in advanced non-small-cell lung cancer patients with a programmed …

Cost-effectiveness of atezolizumab combination therapy for first-line treatment of metastatic nonsquamous non–small cell lung cancer in the United States

SD Criss, MJ Mooradian, TR Watson… - JAMA network …, 2019 - jamanetwork.com
Importance Immune checkpoint inhibitor combination therapy has recently become the
standard of care for first-line treatment of metastatic nonsquamous non–small cell lung …

Cost-effectiveness analysis of atezolizumab plus chemotherapy in the first-line treatment of extensive-stage small-cell lung cancer

K Zhou, J Zhou, J Huang, N Zhang, L Bai, Y Yang, Q Li - Lung cancer, 2019 - Elsevier
Objectives A double-blind, placebo-controlled, phase 3 trial has shown atezolizumab plus
chemotherapy in the first-line treatment of extensive-stage small-cell lung cancer could …

Cost-effectiveness of atezolizumab plus chemotherapy for advanced non-small-cell lung cancer

S Lin, S Luo, L Zhong, S Lai, D Zeng, X Rao… - International journal of …, 2020 - Springer
Background Adding atezolizumab to carboplatin/nab-paclitaxel improved progression-free
survival and overall survival in patients with advanced non-squamous non-small-cell lung …

First‐line pembrolizumab for non–small cell lung cancer patients with PD‐L1≥ 50% in a multicenter real‐life cohort: The PEMBREIZH study

K Amrane, M Geier, R Corre, H Léna… - Cancer …, 2020 - Wiley Online Library
Background The KEYNOTE‐024 trial demonstrated that pembrolizumab, a PD‐1 inhibitor,
significantly improves progression‐free survival (PFS) and overall survival (OS) in selected …