Nitric oxide synthase, which generates the physiological messenger molecule nitric oxide,
and its associated NADPH diaphorase (NADPHd) activity are distributed throughout …

Various mutations in humans and animals lead to the selective and progressive
degeneration of motoneurons, resulting in muscular weakness, subsequent paralysis, and …

Nitric oxide has a tantalizing role in health and disease: while many of its wide-ranging
effects are well known, there remains much more to explore and to learn about the …

In adult spinal motoneurons, retrograde cell death is induced by ventral root avulsion. A
lethal effect of nitric oxide has been implicated, since nitric oxide synthase (NOS) is …

Rapid and massive death of motoneurons occurs following axotomy in neonatal mammals.
This likely results from the neurons being deprived of access to target-derived trophic …

The neuronal isoform of nitric oxide synthase (nNOS), a NADPH-dependent diaphorase, is
considered to play a role in motoneuron death induced by sciatic nerve transection in …

This review tries to survey the expression patterns of inducible transcription factors (ITFs) of
the Jun (c-Jun, JunB, JunD) and Fos (c-Fos, FosB, Fra) families as well as of zinc finger …

Nitric oxide synthase (NOS) activity and NO‐mediated cGMP synthesis were studied in the
rat forebrain of control animals and animals which had received a unilateral lesioning of …

The cytotoxic effects of glutamate via the N‐methyl‐D‐aspartate (NMDA) receptor have been
suggested to take part in the events leading to death of motoneurons after neonatal …

Melatonin is a widely distributed and important signal molecule that occurs in unicellular
organisms, plants, and fungi in addition to animals and humans. It is the main hormone of …