How can machine learning and multiscale modeling benefit ocular drug development?
The eyes possess sophisticated physiological structures, diverse disease targets, limited
drug delivery space, distinctive barriers, and complicated biomechanical processes …
drug delivery space, distinctive barriers, and complicated biomechanical processes …
Damaging effects of ultraviolet radiation on the cornea
NC Delic, JG Lyons, N Di Girolamo… - Photochemistry and …, 2017 - Wiley Online Library
The cornea sits at the anterior aspect of the eye and, like the skin, is highly exposed to
ultraviolet radiation (UVR). The cornea blocks a significant proportion of UVB from reaching …
ultraviolet radiation (UVR). The cornea blocks a significant proportion of UVB from reaching …
On the shell model for human eye in Glaucoma disease
A new mechanical and analytical models of the human eye is presented in order to study
Glaucoma disease and its complications. Mechanical modeling of the human eye is …
Glaucoma disease and its complications. Mechanical modeling of the human eye is …
Characterization of non-linear mechanical behavior of the cornea
The objective of this study was to evaluate which hyperelastic model could best describe the
non-linear mechanical behavior of the cornea, in order to characterize the capability of the …
non-linear mechanical behavior of the cornea, in order to characterize the capability of the …
Noninvasive measurement of wave speed of porcine cornea in ex vivo porcine eyes for various intraocular pressures
The objective of this study was to extend an ultrasound surface wave elastography (USWE)
technique for noninvasive measurement of ocular tissue elastic properties. In particular, we …
technique for noninvasive measurement of ocular tissue elastic properties. In particular, we …
[HTML][HTML] Cataract surgery on post radial keratotomy patients
A Meduri, M Urso, GA Signorino… - International Journal …, 2017 - ncbi.nlm.nih.gov
This study aims to evaluate and to compare three different approaches of cataract surgery to
patients with previous radial keratotomy (RK), and to analyze the mechanical properties of …
patients with previous radial keratotomy (RK), and to analyze the mechanical properties of …
Biomechanical simulation of stress concentration and intraocular pressure in corneas subjected to myopic refractive surgical procedures
PJ Shih, IJ Wang, WF Cai, JY Yen - Scientific reports, 2017 - nature.com
Recent advances in the analysis of corneal biomechanical properties remain difficult to
predict the structural stability before and after refractive surgery. In this regard, we applied …
predict the structural stability before and after refractive surgery. In this regard, we applied …
The applications of finite element analysis in proximal humeral fractures
Y Ye, W You, W Zhu, J Cui, K Chen… - … methods in medicine, 2017 - Wiley Online Library
Proximal humeral fractures are common and most challenging, due to the complexity of the
glenohumeral joint, especially in the geriatric population with impacted fractures, that the …
glenohumeral joint, especially in the geriatric population with impacted fractures, that the …
Estimation of scleral mechanical properties from air-puff optical coherence tomography
D Bronte-Ciriza, JS Birkenfeld, A de la Hoz… - Biomedical Optics …, 2021 - opg.optica.org
We introduce a method to estimate the biomechanical properties of the porcine sclera in
intact eye globes ex vivo, using optical coherence tomography that is coupled with an air …
intact eye globes ex vivo, using optical coherence tomography that is coupled with an air …
Development and challenges in finite element modelling of post-installed anchors in concrete
Finite element analysis (FEA) has been used as a successful supplement to experimental
testing in various studies for simulation of anchorage behaviour. Throughout the years …
testing in various studies for simulation of anchorage behaviour. Throughout the years …