Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression

J Wei, M Li, C Xue, S Chen, L Zheng, H Deng… - Journal of Experimental …, 2023 - Springer
Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are
covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back …

[HTML][HTML] The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy

J Li, G Zhang, CG Liu, X Xiang, MTN Le, G Sethi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Exosomes are multifunctional regulators of intercellular communication by carrying various
messages under both physiological and pathological status of cancer patients …

Exosomal non-coding RNAs: new insights into the biology of hepatocellular carcinoma

Q Zhang, H Li, Y Liu, J Li, C Wu, H Tang - Current Oncology, 2022 - mdpi.com
Exosomes, extracellular vesicles with a diameter of 40 to 160 nm, are among the smallest
extracellular vesicles released by cells. They deliver different cargoes, including proteins …

Recent advances of exosomal circRNAs in cancer and their potential clinical applications

Q Yi, J Yue, Y Liu, H Shi, W Sun, J Feng… - Journal of translational …, 2023 - Springer
Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed,
uninterrupted loop. The expression of circRNA differs among cell types and tissues, and …

Cancer immunotherapy elicited by immunogenic cell death based on smart nanomaterials

M Yang, C Zhang, R Wang, X Wu, H Li… - Small Methods, 2023 - Wiley Online Library
Cancer immunotherapy has been a revolutionary cancer treatment modality because it can
not only eliminate primary tumors but also prevent metastases and recurrent tumors …

CircPTEN suppresses human clear cell renal carcinoma progression and resistance to mTOR inhibitors by targeting epigenetic modification

Y Zhan, Y Liu, R Yang, Q Chen, F Teng, Y Huang… - Drug Resistance …, 2023 - Elsevier
Renal cell carcinoma (RCC) is known to be the most commonly diagnosed kidney cancer.
Clear cell RCC (ccRCC) represents approximately 85% of diagnosed RCC cases. Targeted …

Exosomal Circ-MEMO1 promotes the progression and aerobic glycolysis of non-small cell lung cancer through targeting MiR-101-3p/KRAS axis

C Ding, G Xi, G Wang, D Cui, B Zhang, H Wang… - Frontiers in …, 2020 - frontiersin.org
Circular RNA mediator of cell motility 1 (circ-MEMO1) was identified as an oncogene in non-
small cell lung cancer (NSCLC). Nevertheless, the working mechanism behind circ-MEMO1 …

Exosomal circRNAs: emerging players in tumor metastasis

H Zhou, X He, Y He, C Ou, P Cao - Frontiers in cell and …, 2021 - frontiersin.org
Metastasis is an important feature of malignant tumors, and is the primary cause of poor
prognosis and treatment failure, in addition to representing a potentially fatal challenge for …

Exosomes in the tumor microenvironment: Promoting cancer progression

Y Jin, J Xing, K Xu, D Liu, Y Zhuo - Frontiers in immunology, 2022 - frontiersin.org
Exosomes, which are extracellular vesicles produced by endosomes, are important
performers of intercellular communication functions. For more than three decades, there has …