Cancer immunotherapies targeting adaptive immune checkpoints have substantially
improved patient outcomes across multiple metastatic and treatment-refractory cancer types …

The cytotoxic activity of myeloid cells is regulated by a balance of signals that are transmitted
through inhibitory and activating receptors. The Cluster of Differentiation 47 (CD47) protein …

The adaptive immune checkpoints such as PD-1 (programmed death-1)/PD-L1
(programmed death-ligand 1) play an important role in cancer immunotherapy, whereas …

Nanoparticle‐based phototherapies, such as photothermal therapy (PTT) and photodynamic
therapy (PDT), exhibit strong efficacy, minimal invasion and negligible side effects in tumor …

The development of a wide range of novel antineoplastic therapies has improved the
prognosis for patients with a wide range of malignancies, which has increased the number …

Simple Summary Patients with advanced melanoma are often treated with v-raf murine
sarcoma viral oncogene homolog B1 (BRAF) inhibitors. Although these agents prolong life …

Importance Cardiovascular adverse events (CVAEs) after treatment with BRAF and MEK
inhibitors in patients with melanoma remain incompletely characterized. Objective To …

Timely removal of dying or pathogenic cells by phagocytes is essential to maintaining host
homeostasis. Phagocytes execute the clearance process with high fidelity while sparing …

This manuscript investigates cabozantinib, vandetanib, pralsetinib, and selpercatinib, four
tyrosine kinase inhibitors (TKIs), which are used to treat advanced and/or metastatic …

Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high
heterogeneity that drives tumor aggressiveness. Melanoma plasticity consists of two distinct …