Anticancer Potential of the S‐Heterocyclic Ring Containing Drugs and its Bioactivation to Reactive Metabolites

S Maji, B Debnath, S Panda, T Manna… - Chemistry & …, 2024 - Wiley Online Library
Sulfur‐containing heterocyclic derivatives have been disclosed for binding with a wide
range of cancer‐specific protein targets. Various interesting derivatives of sulfur‐containing …

Fabrication, physicochemical characterization and theoretical studies of some new mixed ligands complexes based on N-(1H-benzimidazol-2-yl)-guanidine and 1, 10 …

AM Abu-Dief, T El‐Dabea, RM El-Khatib… - Journal of Molecular …, 2024 - Elsevier
The fabrication and structural identification of mixed ligand chelates resulting from 1-(1H-
benzimidazol-2-yl) guanidine (BIG= main ligand) and 1, 10-Phenanthroline …

Synthesis, characterization, biological applications, and molecular docking studies of some transition metal complexes with azo dye ligand derived from 5-methyl …

KJ Al-Adilee, SH Jawad, HAK Kyhoiesh… - Journal of Molecular …, 2024 - Elsevier
Metal complexes for Pd (II) and Pt (IV) ions were prepared and spectral identified using a
new heterocyclic azo dye ligand 2-[2′-(3, 4-dimethyl carboxy phenyl) azo]-5-methyl …

Microwave and ultrasound-assisted green protocols for 5-methylthiazole induced Betti bases: molecular docking, in-silico pharmacokinetics, and anticancer activity …

OA Lotlikar, SS Gurav, SN Dandekar… - … Chemistry Letters and …, 2024 - Taylor & Francis
Herein, we describe an efficient one-pot three-component microwave and ultrasound-
endorsed approaches for synthesizing distinct 5-methylthiazole induced Betti bases (5 …

Exploring the therapeutic potentials of bidentate ligands derived from benzohydrazide and their mononuclear transition metal complexes: insights from computational …

B Kumar, J Devi, P Saini, D Khurana, K Singh… - Research on Chemical …, 2024 - Springer
In the twenty-first century, we are witnessed of a large number of infectious ailments which
spread very quickly worldwide and effect the public health significantly. Thus, in the current …

[HTML][HTML] Synthesis, anticancer for prostate cancer cells and antibacterial activity of new diazepine derivatives

NG Fahad, NH Imran, HAK Kyhoiesh… - Results in …, 2023 - Elsevier
In the current study, four new benzodiazepine derivatives were synthesized via a reaction of
o-phenylenediamine with some chalcone derivatives. The synthesized compounds were …

Benzothiazole Derivatives of Chitosan and Their Derived Nanoparticles: Synthesis and In Vitro and In Vivo Antibacterial Effects

TV Shakola, VV Rubanik, VV Rubanik Jr, AV Kurliuk… - Polymers, 2023 - mdpi.com
In this work, we focused on synthesizing and assessing novel chitosan-based antibacterial
polymers and their nanoparticles by incorporating benzothiazole substituents. The growing …

Synthesis, Characterization, in silico DFT, Molecular docking, ADMET Profiling Studies and Toxicity Predictions of Ag (I) Complex Derived from 4‐Aminoacetophenone

HAK Kyhoiesh, HM Hassan - ChemistrySelect, 2024 - Wiley Online Library
The reaction of the synthesized (E)‐1‐(4‐((2, 4‐dihydroxy‐6‐methylphenyl) diazenyl)
phenyl) ethan‐1‐one,(DMPDE) ligand with Ag (I) ion at room temperature resulted in the …

Development of new thiazole‐guanidine complexes as rapid and recoverable catalysts for the synthesis of 6‐piperidin‐dihydro‐thia‐hexaaza‐s‐indacene derivatives …

MAEAAA El‐Remaily, O Elhady… - Applied …, 2024 - Wiley Online Library
In this study, the focus was on synthesizing metal chelates of Fe (III), Ni (II), and Pd (II) using
thiazole‐guanidine derivatives. Various spectral and analytical methods were employed to …

Investigation of solvatochromic, optical, organic field effect transistor (OFET), antibacterial, and molecular bonding of some azothiazolidine-2, 4-dione (AZO-TZD) dyes

HY Nyaki, NO Mahmoodi, HT Nahzomi - Journal of Photochemistry and …, 2024 - Elsevier
Here, new AZO-TZD derivatives (1− 11) were synthesized using cellulose sulphuric acid
(CSA) as a catalyst to prepare diazonium salts and Knoevenagel condensation to produce …