The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin,
specializing in the transport of oxygen. With a total number of approximately 25 trillion cells …

Diabetes mellitus (DM) is a systemic metabolic disease that affects 463 million adults
worldwide and is a leading cause of cardiovascular disease, blindness, nephropathy …

Very long-chain saturated fatty acids and diabetes and cardi... : Current Opinion in Lipidology
Very long-chain saturated fatty acids and diabetes and cardiovascular disease : Current …

Ceramide is a critical bioactive lipid involved in diverse cellular processes. It has been
proposed to regulate cellular processes by influencing membrane properties and by directly …

Sphingolipids have emerged as bioactive lipids involved in the regulation of many
physiological and pathological processes. In the retina, they have been established to …

The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and
ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular …

Microglia are important for brain homeostasis and immunity, but their role in regulating
vigilance remains unclear. We employed genetic, physiological, and metabolomic methods …

Extracellular vesicles (EVs) are shed from the plasma membrane, but the regulation and
function of these EVs remain unclear. We found that oxidative stress induced by H2O2 in …

Ceramide is the simplest precursor of sphingolipids and is involved in a variety of biological
functions ranging from apoptosis to the immune responses. Although ceramide is a minor …