Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Parasitic protozoa of the phylum Apicomplexa cause a range of human and animal
diseases. Their complex life cycles–often heteroxenous with sexual and asexual phases in …

The most severe form of malaria is caused by Plasmodium falciparum. These parasites
invade human erythrocytes, and an essential step in this process involves the ligand PfRh5 …

The phylum Apicomplexa comprises important eukaryotic parasites that invade host tissues
and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin …

During host infection, Toxoplasma gondii and related unicellular parasites move using
gliding, which differs fundamentally from other known mechanisms of eukaryotic cell motility …

Extensive control efforts have significantly reduced malaria cases and deaths over the past
two decades, but in recent years, coupled with the COVID-19 pandemic, success has …

Apicomplexa encompasses a large number of intracellular parasites infecting a wide range
of animals. Cyclic nucleotide signaling is crucial for a variety of apicomplexan life stages and …

Living organisms routinely navigate their surroundings in search of better conditions, more
food, or to avoid predators. Typically, animals do so by integrating sensory cues from the …

With emerging resistance to frontline treatments, it is vital that new antimalarial drugs are
identified to target Plasmodium falciparum. We have recently described a compound …

Toxoplasma gondii is a protozoan apicomplexan parasite that uses an adhesion-dependent
mode of motility termed gliding to access host cells and disseminate into tissues. Previous …