Perspectives on usage of functional nanomaterials in antimicrobial therapy for antibiotic-resistant bacterial infections
The clinical applications of nanotechnology are emerging as widely popular, particularly as
a potential treatment approach for infectious diseases. Diseases associated with multiple …
a potential treatment approach for infectious diseases. Diseases associated with multiple …
Hierarchical nanomaterials assembled from peptoids and other sequence-defined synthetic polymers
In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures
plays an essential role in the construction of functional biomaterials. To develop synthetic …
plays an essential role in the construction of functional biomaterials. To develop synthetic …
Nanoparticle mediated RNA delivery for wound healing
Wound healing is a complicated physiological process that comprises various steps,
including hemostasis, inflammation, proliferation, and remodeling. The wound healing …
including hemostasis, inflammation, proliferation, and remodeling. The wound healing …
Pathophysiology of fibrosis in the vocal fold: current research, future treatment strategies, and obstacles to restoring vocal fold pliability
Y Kumai - International journal of molecular sciences, 2019 - mdpi.com
Communication by voice depends on symmetrical vibrations within the vocal folds (VFs) and
is indispensable for various occupations. VF scarring is one of the main reasons for …
is indispensable for various occupations. VF scarring is one of the main reasons for …
Reversal of vocal fold mucosal fibrosis using siRNA against the collagen-specific chaperone Serpinh1
Y Kishimoto, M Yamashita, A Wei, Y Toya, S Ye… - … Therapy-Nucleic Acids, 2019 - cell.com
Vocal fold (VF) mucosal fibrosis results in substantial voice impairment and is recalcitrant to
current treatments. To reverse this chronic disorder, anti-fibrotic therapies should target the …
current treatments. To reverse this chronic disorder, anti-fibrotic therapies should target the …
Drug delivery systems for wound healing treatment of upper airway injury
Introduction Endotracheal intubation is a common procedure to maintain an open airway
with risks for traumatic injury. Pathological changes resulting from intubation can cause …
with risks for traumatic injury. Pathological changes resulting from intubation can cause …
The effects of cytosporone‐B, a novel antifibrotic agent, on vocal fold fibroblasts
N Hiwatashi, S Mukudai, R Bing… - The …, 2018 - Wiley Online Library
Objectives/Hypothesis Our laboratory recently described NR4A1 as an endogenous inhibitor
of TGF‐β–induced vocal fold (VF) fibrosis. Our prior report described the temporal …
of TGF‐β–induced vocal fold (VF) fibrosis. Our prior report described the temporal …
Acute Effects of Steroids on Vocal Fold Epithelium Post‐injury in a Preclinical Model
G Gartling, L Sayce, Z Zimmerman, A Slater… - The …, 2024 - Wiley Online Library
Introduction Glucocorticoids (GCs) are commonly prescribed for laryngeal indications due to
their potent anti‐inflammatory properties. However, GCs effect on vocal fold (VF) epithelial …
their potent anti‐inflammatory properties. However, GCs effect on vocal fold (VF) epithelial …
Quantifying vocal fold wound‐healing biomechanical property changes
Objectives Development of novel vocal fold (VF) therapeutics is limited by a lack of
standardized, meaningful outcomes. We hypothesize that automated microindentation …
standardized, meaningful outcomes. We hypothesize that automated microindentation …
Implementing Efficient Peptoid‐Mediated Delivery of RNA‐Based Therapeutics to the Vocal Folds
S Mukudai, I Kraja, R Bing, DM Nalband… - Laryngoscope …, 2019 - Wiley Online Library
Objective We hypothesize that Smad3 is a master regulator of fibrosis in the vocal folds
(VFs) and RNA‐based therapeutics targeting Smad3 hold therapeutic promise. Delivery …
(VFs) and RNA‐based therapeutics targeting Smad3 hold therapeutic promise. Delivery …