Autophagy is a crucial recycling process that is increasingly being recognized as an
important factor in cancer initiation, cancer (stem) cell maintenance as well as the …

Autophagy is an important process of cellular degradation and has been proven to
contribute to tumorigenesis. High-mobility group box 1 (HMGB1) is an abundant nonhistone …

Dysfunctional mitochondria have been shown to enhance cancer cell proliferation, reduce
apoptosis, and increase chemoresistance. Chemoresistance develops in nearly all patients …

Chemoresistance remains as a major hindrance in the treatment of hepatocellular
carcinoma (HCC). High mobility group box protein 1 (HMGB1) enhances autophagic flux …

As a non-histone chromatin-associated protein, high-mobility group box‑1 (HMGB1)
performs a pivotal function in various human diseases, including autoimmune diseases …

Background Circular RNAs (circRNAs) have been closely implicated in competing
endogenous RNA (ceRNA) network among human cancers including non‐small cell lung …

High-mobility group box 1 (HMGB1) has been found to mediate autophagy during
chemotherapy in several cancers. However, whether HMGB1plays a role in autophagy and …

Background: Non-small-cell lung cancer (NSCLC) is a deadly cancer with high mortality
rate. Drug resistance represents a main obstacle in NSCLC treatment. High mobility group …

Background Rheumatoid arthritis fibroblast-like synovial cells (RA-FLS) show resistance to
methotrexate (MTX) treatment. To better understand the mechanisms of this resistance, RA …

Tumour suppressor genes play a cardinal role in the development of a large array of human
cancers, including lung cancer, which is one of the most frequently diagnosed cancers …