Ultrasonic vocalizations as a tool in studying emotional states in rodent models of social behavior and brain disease

N Simola, S Granon - Neuropharmacology, 2019 - Elsevier
Rodents emit ultrasonic vocalizations (USVs) to communicate the presence of positive or
negative emotional states and to coordinate social interactions. On this basis, USVs are …

Under or absent reporting of light stimuli in testing of anxiety-like behaviors in rodents: the need for standardization

LS Neuwirth, MT Verrengia… - Frontiers in molecular …, 2022 - frontiersin.org
Behavioral neuroscience tests such as the Light/Dark Test, the Open Field Test, the Elevated
Plus Maze Test, and the Three Chamber Social Interaction Test have become both essential …

Prebiotics modulate the microbiota–gut–brain axis and ameliorate cognitive impairment in APP/PS1 mice

S Zhang, S Lv, Y Li, D Wei, X Zhou, X Niu… - European Journal of …, 2023 - Springer
Purpose Prebiotics, including fructo-oligosaccharides (FOS) and galacto-oligosaccharides
(GOS), stimulate beneficial gut bacteria and may be helpful for patients with Alzheimer's …

Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion

LL Martucci, JM Launay, N Kawakami… - Proceedings of the …, 2023 - National Acad Sciences
Oxytocin (OT) is a prominent regulator of many aspects of mammalian social behavior and
stored in large dense-cored vesicles (LDCVs) in hypothalamic neurons. It is released in …

Social dysfunction in the neurodevelopmental model of schizophrenia in male and female rats: Behavioural and biochemical studies

A Potasiewicz, M Holuj, E Litwa, K Gzielo, L Socha… - …, 2020 - Elsevier
Social dysfunction is among the core symptoms of schizophrenia. The neuropeptides
oxytocin (OXT) and vasopressin (VP) are involved in the regulation of social behaviour and …

Effects of ketamine on rat social behavior as analyzed by DeepLabCut and SimBA deep learning algorithms

P Popik, E Cyrano, D Piotrowska, M Holuj… - Frontiers in …, 2024 - frontiersin.org
Traditional methods of rat social behavior assessment are extremely time-consuming and
susceptible to the subjective biases. In contrast, novel digital techniques allow for rapid and …

Influence of the dose of ketamine used on schizophrenia-like symptoms in mice: A correlation study with TH, GAD67, and PPAR-γ

T Rodrigues, GN Bressan, BN Krum… - Pharmacology …, 2023 - Elsevier
Schizophrenia is a chronic, debilitating mental illness that has not yet been completely
understood. In this study, we aimed to investigate the effects of different doses of ketamine, a …

Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice

E de Oliveira Ferreira, JMP Gomes… - Behavioural …, 2023 - journals.lww.com
Autism spectrum disorder (ASD) describes a heterogeneous group of neurodevelopmental
conditions characterized by deficits in social communication and repetitive behaviors …

Altered circadian activity and sleep/wake rhythms in the stable tubule only polypeptide (STOP) null mouse model of schizophrenia

S Deurveilher, KR Ko, BSC Saumure, GS Robertson… - Sleep, 2021 - academic.oup.com
Sleep and circadian rhythm disruptions commonly occur in individuals with schizophrenia.
Stable tubule only polypeptide (STOP) knockout (KO) mice show behavioral impairments …

[HTML][HTML] Pro-social and pro-cognitive effects of LIT-001, a novel oxytocin receptor agonist in a neurodevelopmental model of schizophrenia

D Piotrowska, A Potasiewicz, P Popik… - European …, 2024 - Elsevier
Social and cognitive dysfunctions are the most persistent symptoms of schizophrenia. Since
oxytocin (OXT) is known to play a role in social functions and modulates cognitive …