Communication by voice depends on symmetrical vibrations within the vocal folds (VFs) and
is indispensable for various occupations. VF scarring is one of the main reasons for …

Vocal fold (VF) fibrosis is a major cause of intractable voice-related disability and reduced
quality of life. Excision of fibrotic regions is suboptimal and associated with scar recurrence …

Background Physical forces, such as mechanical stress, are essential for tissue homeostasis
and influence gene expression of cells. In particular, the fibroblast has demonstrated …

Vocal folds are important to daily breathing, speech, and swallowing functions. Irreversible
changes to the vocal fold mucosa, such as scarring and atrophy, require regenerative …

Objectives Vocal fold (VF) scarring and laryngeal stenosis are a significant clinical
challenge. Excessive scar formation causes low voice quality or even life‐threatening …

Non-thermal plasma (NTP) is a promising biomedical tool for application to wound healing.
However, there is limited scientific evidence that confirms its efficacy to inhibit scar formation …

Scarring of the vocal fold lamina propria (LP) can cause considerable voice disorders due to
reduced pliability in scar tissue, attributed in part to abnormal extracellular matrix (ECM) …

Vocal fold (VF) mucosal fibrosis results in substantial voice impairment and is recalcitrant to
current treatments. To reverse this chronic disorder, anti-fibrotic therapies should target the …

Objective Glucocorticoids (GCs) modulate multiple cellular activities including inflammatory
and fibrotic responses. Outcomes of GC treatment for laryngeal disease vary, affording …

Background Vocal fold (VF) scarring remains a therapeutic dilemma and challenge in
modern laryngology. To facilitate corresponding research, we aimed to establish an in vitro …