Non-equilibrium steady states in catalysis, molecular motors, and supramolecular materials: why networks and language matter

I Aprahamian, SM Goldup - Journal of the American Chemical …, 2023 - ACS Publications
All chemists are familiar with the idea that, at equilibrium steady state, the relative
concentrations of species present in a system are predicted by the corresponding …

Mitochondria: in sickness and in health

J Nunnari, A Suomalainen - Cell, 2012 - cell.com
Mitochondria perform diverse yet interconnected functions, producing ATP and many
biosynthetic intermediates while also contributing to cellular stress responses such as …

Computational design of mechanically coupled axle-rotor protein assemblies

A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu… - Science, 2022 - science.org
Natural molecular machines contain protein components that undergo motion relative to
each other. Designing such mechanically constrained nanoscale protein architectures with …

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

M Bonora, MR Wieckowski, C Chinopoulos, O Kepp… - Oncogene, 2015 - nature.com
The term mitochondrial permeability transition (MPT) is commonly used to indicate an abrupt
increase in the permeability of the inner mitochondrial membrane to low molecular weight …

OXPHOS mutations and neurodegeneration

WJH Koopman, F Distelmaier, JAM Smeitink… - The EMBO …, 2013 - embopress.org
Mitochondrial oxidative phosphorylation (OXPHOS) sustains organelle function and plays a
central role in cellular energy metabolism. The OXPHOS system consists of 5 multisubunit …

Vanadium and proteins: Uptake, transport, structure, activity and function

JC Pessoa, E Garribba, MFA Santos… - Coordination chemistry …, 2015 - Elsevier
Vanadium is an element ubiquitously present in our planet's crust and thus there are several
organisms that use vanadium for activity or function of proteins. Examples are the vanadium …

FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models

J Deng, P Wang, X Chen, H Cheng… - Proceedings of the …, 2018 - National Acad Sciences
FUS (fused in sarcoma) proteinopathy is a group of neurodegenerative diseases
characterized by the formation of inclusion bodies containing the FUS protein, including …

[HTML][HTML] Biochemistry, electron transport chain

M Ahmad, A Wolberg, CI Kahwaji - 2018 - europepmc.org
The electron transport chain is a series of four protein complexes that couple redox
reactions, creating an electrochemical gradient that leads to the creation of ATP in a …

Toward artificial cells: novel advances in energy conversion and cellular motility

S Jeong, HT Nguyen, CH Kim, MN Ly… - Advanced Functional …, 2020 - Wiley Online Library
The demand to discover every single cellular component has been continuously increasing
along with the development of biological techniques. The bottom‐up approach to construct a …

Minimal physicalism as a scale-free substrate for cognition and consciousness

C Fields, JF Glazebrook, M Levin - Neuroscience of …, 2021 - academic.oup.com
Theories of consciousness and cognition that assume a neural substrate automatically
regard phylogenetically basal, nonneural systems as nonconscious and noncognitive. Here …