Aging-induced pathological alterations of the circulatory system play a critical role in
morbidity and mortality of older adults. While the importance of cellular and molecular …

There has been an increasing appreciation of the role of vascular contributions to cognitive
impairment and dementia (VCID) associated with old age. Strong preclinical and …

Background Acute subdural haematomas (ASDH) occur commonly following traumatic brain
injury and may be evacuated by either craniotomy (CR) or decompressive craniectomy (DC) …

Background Acute subdural hematoma (SDH) is a major cause of morbidity after severe
traumatic brain injury. Surgical evacuation of the hematoma, either via craniotomy or …

Objectives Acute subdural haematoma (ASDH) is a devastating pathology commonly found
on CT brain scans of patients with traumatic brain injury. The role of surgical intervention in …

The use of mouse models in traumatic brain injury (TBI) has several advantages compared
to other animal models including low cost of breeding, easy maintenance, and innovative …

Background Subdural hematomas (SDHs) are a common and dangerous condition, with
potential for a rapid rise in incidence given the aging US population, but the magnitude of …

There are two controversial surgery methods which are traditionally used: craniotomy and
decompressive craniectomy. The aim of this study was to evaluate the efficacy and …

Background Surgery for elderly patients with acute subdural hematomas (ASDH) is
controversial, because postoperative mortality rates are reported to be high and long-term …

Objective We investigated the association of decompressive craniectomy (DC) and
osteoplastic craniotomy (OC) with outcomes in consecutive patients undergoing surgical …