Preventive strategies for mental health
Available treatment methods have shown little effect on the burden associated with mental
health disorders. We review promising universal, selective, and indicated preventive mental …
health disorders. We review promising universal, selective, and indicated preventive mental …
A review of vulnerability and risks for schizophrenia: Beyond the two hit hypothesis
Schizophrenia risk has often been conceptualized using a model which requires two hits in
order to generate the clinical phenotype—the first as an early priming in a genetically …
order to generate the clinical phenotype—the first as an early priming in a genetically …
Association of neurocognition with transition to psychosis: baseline functioning in the second phase of the North American Prodrome Longitudinal Study
LJ Seidman, DI Shapiro, WS Stone… - JAMA …, 2016 - jamanetwork.com
Importance Neurocognition is a central characteristic of schizophrenia and other psychotic
disorders. Identifying the pattern and severity of neurocognitive functioning during the “near …
disorders. Identifying the pattern and severity of neurocognitive functioning during the “near …
Evolving notions of schizophrenia as a developmental neurocognitive disorder
LJ Seidman, AF Mirsky - Journal of the International …, 2017 - cambridge.org
We review the changing conceptions of schizophrenia over the past 50 years as it became
understood as a disorder of brain function and structure in which neurocognitive dysfunction …
understood as a disorder of brain function and structure in which neurocognitive dysfunction …
Early interventions in risk groups for schizophrenia: what are we waiting for?
Intervention strategies in adolescents at ultra high-risk (UHR) for psychosis are promising for
reducing conversion to overt illness, but have only limited impact on functional outcome …
reducing conversion to overt illness, but have only limited impact on functional outcome …
Prenatal maternal stress and the cascade of risk to schizophrenia spectrum disorders in offspring
Abstract Purpose of Review Disruptions in fetal development (via genetic and environmental
pathways) have been consistently associated with risk for schizophrenia in a variety of …
pathways) have been consistently associated with risk for schizophrenia in a variety of …
The Danish High Risk and Resilience Study–VIA 7-a cohort study of 520 7-year-old children born of parents diagnosed with either schizophrenia, bipolar disorder or …
Background Severe mental illnesses like schizophrenia and bipolar disorder are known to
be diseases that to some extent, but not entirely can be understood genetically. The …
be diseases that to some extent, but not entirely can be understood genetically. The …
Comprehensive characterization of motor and coordination functions in three adolescent wild-type mouse strains
A Eltokhi, B Kurpiers, C Pitzer - Scientific reports, 2021 - nature.com
Neuropsychiatric disorders are often associated with motor and coordination abnormalities
that have important implications on the etiology, pathophysiology, and management of these …
that have important implications on the etiology, pathophysiology, and management of these …
Functional connectome organization predicts conversion to psychosis in clinical high-risk youth from the SHARP program
The emergence of prodromal symptoms of schizophrenia and their evolution into overt
psychosis may stem from an aberrant functional reorganization of the brain during …
psychosis may stem from an aberrant functional reorganization of the brain during …
Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls
Psychotic disorders including schizophrenia are commonly accompanied by cognitive
deficits. Recent studies have reported negative genetic correlations between schizophrenia …
deficits. Recent studies have reported negative genetic correlations between schizophrenia …