SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization
In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …
In Vivo Metabolic Imaging of [1‐13C]Pyruvate‐d3 Hyperpolarized By Reversible Exchange With Parahydrogen**
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …
Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications
OG Salnikov, DB Burueva, IV Skovpin… - Mendeleev …, 2023 - Elsevier
Signal amplification by reversible exchange (SABRE) is a rapidly developing nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
Hyperpolarising pyruvate through signal amplification by reversible exchange (SABRE)
W Iali, SS Roy, BJ Tickner, F Ahwal… - Angewandte …, 2019 - Wiley Online Library
Hyperpolarisation methods that premagnetise agents such as pyruvate are currently
receiving significant attention because they produce sensitivity gains that allow disease …
receiving significant attention because they produce sensitivity gains that allow disease …
Micron-scale NV-NMR spectroscopy with signal amplification by reversible exchange
Optically probed nitrogen-vacancy (NV)) quantum defects in diamond can detect nuclear
magnetic resonance (NMR) signals with high-spectral resolution from micron-scale sample …
magnetic resonance (NMR) signals with high-spectral resolution from micron-scale sample …
Over 20% Carbon-13 Polarization of Perdeuterated Pyruvate Using Reversible Exchange with Parahydrogen and Spin-Lock Induced Crossing at 50 μT
Carbon-13 hyperpolarized pyruvate is about to become the next-generation contrast agent
for molecular magnetic resonance imaging of cancer and other diseases. Here, efficient and …
for molecular magnetic resonance imaging of cancer and other diseases. Here, efficient and …
In Situ Hyperpolarization Enables 15N and 13C Benchtop NMR at Natural Isotopic Abundance
R Kircher, J Xu, DA Barskiy - Journal of the American Chemical …, 2023 - ACS Publications
Without employing isotopic labeling, we demonstrate the generation of 15N and 13C NMR
signals for molecules containing− NH2 motifs using benchtop NMR spectrometers (1–1.4 T) …
signals for molecules containing− NH2 motifs using benchtop NMR spectrometers (1–1.4 T) …
Quasi-continuous production of highly hyperpolarized carbon-13 contrast agents every 15 seconds within an MRI system
AB Schmidt, M Zimmermann, S Berner… - Communications …, 2022 - nature.com
Hyperpolarized contrast agents (HyCAs) have enabled unprecedented magnetic resonance
imaging (MRI) of metabolism and pH in vivo. Producing HyCAs with currently available …
imaging (MRI) of metabolism and pH in vivo. Producing HyCAs with currently available …
Analysis of chemical exchange in iridium N-heterocyclic carbene complexes using heteronuclear parahydrogen-enhanced NMR
The signal amplification by reversible exchange process (SABRE) enhances NMR signals
by unlocking hidden polarization in parahydrogen through interactions with to-be …
by unlocking hidden polarization in parahydrogen through interactions with to-be …
Continuous hyperpolarization with parahydrogen in a membrane reactor
S Lehmkuhl, M Wiese, L Schubert, M Held… - Journal of Magnetic …, 2018 - Elsevier
Hyperpolarization methods entail a high potential to boost the sensitivity of NMR. Even
though the “Signal Amplification by Reversible Exchange”(SABRE) approach uses para …
though the “Signal Amplification by Reversible Exchange”(SABRE) approach uses para …