Protein-based bioactive coatings: from nanoarchitectonics to applications
C Fu, Z Wang, X Zhou, B Hu, C Li, P Yang - Chemical Society Reviews, 2024 - pubs.rsc.org
Protein-based bioactive coatings have emerged as a versatile and promising strategy for
enhancing the performance and biocompatibility of diverse biomedical materials and …
enhancing the performance and biocompatibility of diverse biomedical materials and …
Material approaches to active tissue mechanics
Communities of epithelial cells communicate through intercellular interactions, allowing
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …
Integer topological defects organize stresses driving tissue morphogenesis
P Guillamat, C Blanch-Mercader, G Pernollet… - Nature materials, 2022 - nature.com
Tissues acquire function and shape via differentiation and morphogenesis. Both processes
are driven by coordinating cellular forces and shapes at the tissue scale, but general …
are driven by coordinating cellular forces and shapes at the tissue scale, but general …
Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection
Glutaminase (GLS), which deaminates glutamine to form glutamate, is a mitochondrial
tetrameric protein complex. Although inorganic phosphate (Pi) is known to promote GLS …
tetrameric protein complex. Although inorganic phosphate (Pi) is known to promote GLS …
Contractility, focal adhesion orientation, and stress fiber orientation drive cancer cell polarity and migration along wavy ECM substrates
Contact guidance is a powerful topographical cue that induces persistent directional cell
migration. Healthy tissue stroma is characterized by a meshwork of wavy extracellular matrix …
migration. Healthy tissue stroma is characterized by a meshwork of wavy extracellular matrix …
Tailoring cryo-electron microscopy grids by photo-micropatterning for in-cell structural studies
M Toro-Nahuelpan, I Zagoriy, F Senger, L Blanchoin… - Nature …, 2020 - nature.com
Spatially controlled cell adhesion on electron microscopy supports remains a bottleneck in
specimen preparation for cellular cryo-electron tomography. Here, we describe contactless …
specimen preparation for cellular cryo-electron tomography. Here, we describe contactless …
Convergence of microengineering and cellular self-organization towards functional tissue manufacturing
J Laurent, G Blin, F Chatelain, V Vanneaux… - Nature Biomedical …, 2017 - nature.com
Technical progress in materials science and bioprinting has for the past few decades
fostered considerable advances in medicine. More recently, the understanding of the …
fostered considerable advances in medicine. More recently, the understanding of the …
Nanoscale surface topography reduces focal adhesions and cell stiffness by enhancing integrin endocytosis
Both substrate stiffness and surface topography regulate cell behavior through
mechanotransduction signaling pathways. Such intertwined effects suggest that engineered …
mechanotransduction signaling pathways. Such intertwined effects suggest that engineered …
Engineering a tunable micropattern‐array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ
The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of
physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of …
physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of …
How cells respond to environmental cues–insights from bio-functionalized substrates
Biomimetic materials have long been the (he) art of bioengineering. They usually aim at
mimicking in vivo conditions to allow in vitro culture, differentiation and expansion of cells …
mimicking in vivo conditions to allow in vitro culture, differentiation and expansion of cells …