Muscle tissue may be damaged following intense prolonged training as a consequence of
both metabolic and mechanical factors. Serum levels of skeletal muscle enzymes or proteins …

Areas of general agreement Total creatine kinase (CK) levels depend on age, gender, race,
muscle mass, physical activity and climatic condition. High levels of serum CK in apparently …

How to manage a patient who has an elevated serum creatine kinase (CK) level but no or
insignificant muscle-related signs and symptoms is a clinical conundrum. The authors …

Total creatin kinase (CK) and lactate dehydrogenase (LDH) serum levels depend on age,
gender, race, muscle mass, physical activity, and climatic conditions. High CK serum levels …

Objective: To provide evidence‐based guidelines to general neurologists for the
assessment of patients with pauci‐or asymptomatic hyperCKemia. Background: Recent …

Abstract Myotonic dystrophy types 1 (DM1) and 2 (DM2) are similar yet distinct autosomal‐
dominant disorders characterized by muscle weakness, myotonia, cataracts, and multiple …

Background and purpose Rhabdomyolysis is a medical emergency characterized by acute
skeletal muscle breakdown with a sudden rise and subsequent fall of serum creatine kinase …

Myotonic dystrophies (dystrophia myotonica, or DM) are inherited disorders characterized by
myotonia and progressive muscle degeneration, which are variably associated with a …

The myotonic disorders are a heterogeneous group of genetically determined diseases that
are unified by the presence of myotonia, which is defined as failure of muscle relaxation after …

Neuromuscular clinicians are frequently asked to evaluate patients referred for
asymptomatic elevations in creatine kinase (CK), a catalytic enzyme that combines creatine …