Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

Tumor-associated macrophages (TAMs) acquire a pro-tumor (M2) phenotype, which
promotes tumor growth, angiogenesis, and metastasis. Certain microRNAs (miRs), such as …

In recent years, nanomedicines have emerged as a promising method for central nervous
system drug delivery, enabling the drugs to overcome the blood-brain barrier and …

Three decades have passed from the initial discovery of a microRNA (miRNA) in
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …

Cadherin-6 (CDH6) is aberrantly expressed in cancer and closely associated with tumor
progression. However, the functions of CDH6 in human osteosarcoma and the molecular …

MicroRNAs (miRNAs) are small and highly conserved non‐coding RNAs that silence target
mRNAs, and compelling evidence suggests that they play an essential role in the …

Tuberculosis (TB) is one of the most fatal infectious diseases and a leading cause of
mortality, with 95% of these deaths occurring in developing countries. The causative agent …

As a biological carrier, exosomes participate in the communication between various kinds of
cells, and can mediate the interactive 'dialogue'between tumor cells and tumor-associated …

Accumulating evidences suggest that longnon-coding RNAs (lncRNAs) play functional roles
in development of different cancers, including cancer initiation and progression. Metastasis …