The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …

Purpose. Although oral delivery has become a widely accepted route of administration of
therapeutic drugs, the gastrointestinal tract presents several formidable barriers to drug …

Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin
and joint manifestations affecting approximately 2% of the population. In this fourth of 6 …

Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the
intestinal mucosa and unknown etiology. In this review, we identified three main eras in the …

There is growing interest in the evaluation of drugs (prescription only medicines and over-
the-counter medicines) as antioxidant prophylactics. Although free radical mechanism in …

This review examines the biological significance, therapeutic potential and mechanism (s) of
action of a range of nitric oxide‐releasing non‐steroidal anti‐inflammatory drugs (NO …

Sulfasalazine and mesalazine (also known as mesalamine; 5-aminosalicylic acid)
preparations have for many years been used for the treatment of IBD (ie ulcerative colitis …

Guidelines of care for the management of psoriasis and psoriatic arthritis Page 1 FROM THE
ACADEMY Guidelines of care for the management of psoriasis and psoriatic arthritis Section 4 …

Extraintestinal manifestations occur in about one-third of patients living with inflammatory
bowel disease (IBD) and may precede the onset of gastrointestinal symptoms by many …

The increasing number of peptide and protein drugs being investigated demands the
development of dosage forms which exhibit site-specific release. Delivery of drugs into …