Chitosan: Structural modification, biological activity and application

W Wang, C Xue, X Mao - International Journal of Biological …, 2020 - Elsevier
Many by-products that are harmful to the environment and human health are generated
during food processing. However, these wastes are often potential resources with high …

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

JD Martin, H Cabral, T Stylianopoulos… - Nature reviews Clinical …, 2020 - nature.com
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …

(Nano) platforms in breast cancer therapy: drug/gene delivery, advanced nanocarriers and immunotherapy

M Ashrafizadeh, A Zarrabi, A Bigham… - Medicinal Research …, 2023 - Wiley Online Library
Breast cancer is the most malignant tumor in women, and there is no absolute cure for it.
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …

Current and emerging applications of saccharide-modified chitosan: a critical review

HKS Panahi, M Dehhaghi, H Amiri, GJ Guillemin… - Biotechnology …, 2023 - Elsevier
Chitin, as the main component of the exoskeleton of Arthropoda, is a highly available natural
polymer that can be processed into various value-added products. Its most important …

[HTML][HTML] The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer

A Masjedi, V Hashemi, M Hojjat-Farsangi… - Biomedicine & …, 2018 - Elsevier
Despite remarkable improvements in cancer treatment approaches, breast cancer is still the
main cause of cancer-related death in women. Its principal cause is the resistance of the …

Biomedical application of chitosan-based nanoscale delivery systems: Potential usefulness in siRNA delivery for cancer therapy

M Ashrafizadeh, M Delfi, F Hashemi, A Zabolian… - Carbohydrate …, 2021 - Elsevier
Gene therapy is an emerging and promising strategy in cancer therapy where small
interfering RNA (siRNA) system has been deployed for down-regulation of targeted gene …

Nanoparticles and targeted drug delivery in cancer therapy

B Bahrami, M Hojjat-Farsangi, H Mohammadi… - Immunology letters, 2017 - Elsevier
Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Polymeric nanoparticle vaccines to combat emerging and pandemic threats

D Wibowo, SHT Jorritsma, ZJ Gonzaga, B Evert… - Biomaterials, 2021 - Elsevier
Subunit vaccines are more advantageous than live attenuated vaccines in terms of safety
and scale-up manufacture. However, this often comes as a trade-off to their efficacy. Over …

Functionalized chitosan for cancer nano drug delivery

Y Zaiki, A Iskandar, TW Wong - Biotechnology Advances, 2023 - Elsevier
Chitosan is a biotechnological derivative of chitin receiving a widespread pharmaceutical
and biomedical applications. It can be used to encapsulate and deliver cancer therapeutics …

The microstructure, antibacterial and antitumor activities of chitosan oligosaccharides and derivatives

D Yu, J Feng, H You, S Zhou, Y Bai, J He, H Cao… - Marine Drugs, 2022 - mdpi.com
Chitosan obtained from abundant marine resources has been proven to have a variety of
biological activities. However, due to its poor water solubility, chitosan application is limited …