Dietary prospects of coconut oil for the prevention and treatment of Alzheimer's disease (AD): A review of recent evidences

SV Ramesh, V Krishnan, S Praveen… - Trends in Food Science & …, 2021 - Elsevier
Background Alzheimer's disease (AD) is a devastating neurodegenerative ailment having
pathological hallmarks of plaques due to amyloid β (Aβ) peptides and neurofibrillary tangles …

[HTML][HTML] Impact of levetiracetam on cognitive impairment, neuroinflammation, oxidative stress, and neuronal apoptosis caused by lipopolysaccharides in rats

V Mani, SR Almutairi - Saudi Pharmaceutical Journal, 2023 - Elsevier
Introduction Neuroinflammation is associated with the elevation of toxic proinflammatory
mediators that promote neurodegeneration and subsequently affect cognition. Causes of …

Neuroprotective role of coconut oil for the prevention and treatment of Parkinson's disease: Potential mechanisms of action

D N. P, MS Kondengadan, SH Sweilam… - Biotechnology and …, 2024 - Taylor & Francis
Neurodegenerative disease (ND) is a clinical condition in which neurons degenerate with a
consequent loss of functions in the affected brain region. Parkinson's disease (PD) is the …

Prenatal hyperhomocysteinemia induces glial activation and alters neuroinflammatory marker expression in infant rat hippocampus

AD Shcherbitskaia, DS Vasilev, YP Milyutina… - Cells, 2021 - mdpi.com
Maternal hyperhomocysteinemia is one of the common complications of pregnancy that
causes offspring cognitive deficits during postnatal development. In this study, we …

[HTML][HTML] Oral lipid-based formulations alter delivery of cannabidiol to different anatomical regions in the brain

A Brookes, A Jewell, W Feng, TD Bradshaw… - International Journal of …, 2023 - Elsevier
Delivery to the brain is a challenging task due to its protection by the blood–brain barrier
(BBB). Lipids and fatty acids are reported to affect the permeability of the BBB, although this …

Physicochemical characterization and fatty acid profiles of testa oils from various coconut (Cocos nucifera L.) genotypes

R Shunmugiah Veluchamy, R Mary… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND Cocos nucifera (L.) is an important plantation crop with immense but
untapped nutraceutical potential. Despite its bioactive potential, the biochemical features of …

Neuroprotective effect of clobenpropit against lipopolysaccharide-induced cognitive deficits via attenuating neuroinflammation and enhancing mitochondrial functions …

V Mani, M Arfeen, HM Ali, AMH Abdel-Moneim… - Brain Sciences, 2021 - mdpi.com
Clobenpropit (CLO), an antagonist on histamine H3 receptors (HH3R), has been shown to
protect NMDA-induced neuronal necrosis in cortical neuronal cell culture from rats. In this …

LPS-induced impairment of Na+/K+-ATPase activity: ameliorative effect of tannic acid in mice

KP Luduvico, L Spohr, MSS de Aguiar… - Metabolic Brain …, 2022 - Springer
Acetylcholine is an excitatory neurotransmitter that modulates synaptic plasticity and
communication, and it is essential for learning and memory processes. This neurotransmitter …

[PDF][PDF] Ciproxifan attenuates the memory impairment induced by lipopolysaccharide through modulation of cholinergic transmission in the mouse brain.

V Mani, M Arfeen, HM Ali… - European Review for …, 2022 - europeanreview.org
OBJECTIVE: We investigated the protective effect of ciproxifan on lipopolysaccharide (LPS)-
induced memory impairment by altering the cholinergic system in a mouse model …

Hibiscetin attenuates lipopolysaccharide-evoked memory impairment by inhibiting BDNF/caspase-3/NF-κB pathway in rodents

SJ Gilani, MNB Jumah, F Fatima, FA Al-Abbasi, M Afzal… - PeerJ, 2024 - peerj.com
This study explores the neuroprotective potential of hibiscetin concerning memory deficits
induced by lipopolysaccharide (LPS) injection in rats. The aim of this study is to evaluate the …