High density lipoprotein structure–function and role in reverse cholesterol transport
S Lund-Katz, MC Phillips - … Transport Proteins: Structure and Function in …, 2010 - Springer
High density lipoprotein (HDL) possesses important anti-atherogenic properties and this
review addresses the molecular mechanisms underlying these functions. The structures and …
review addresses the molecular mechanisms underlying these functions. The structures and …
New insights into the determination of HDL structure by apolipoproteins1: Thematic Review Series: High Density Lipoprotein Structure, Function, and Metabolism
MC Phillips - Journal of lipid research, 2013 - ASBMB
Apolipoprotein (apo) AI is the principal protein component of HDL, and because of its
conformational adaptability, it can stabilize all HDL subclasses. The amphipathic α-helix is …
conformational adaptability, it can stabilize all HDL subclasses. The amphipathic α-helix is …
Structure of membrane-bound α-synuclein studied by site-directed spin labeling
CC Jao, A Der-Sarkissian, J Chen… - Proceedings of the …, 2004 - National Acad Sciences
Many of the proposed physiological functions of α-synuclein, a protein involved in the
pathogenesis of Parkinson's disease, are related to its ability to interact with phospholipids …
pathogenesis of Parkinson's disease, are related to its ability to interact with phospholipids …
[图书][B] Biomolecular EPR spectroscopy
WR Hagen - 2008 - taylorfrancis.com
Comprehensive, Up-to-Date Coverage of Spectroscopy Theory and its Applications to
Biological SystemsAlthough a multitude of books have been published about spectroscopy …
Biological SystemsAlthough a multitude of books have been published about spectroscopy …
Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins
H Saito, S Lund-Katz, MC Phillips - Progress in lipid research, 2004 - Elsevier
Exchangeable apolipoproteins function in lipid transport as structural components of
lipoprotein particles, cofactors for enzymes and ligands for cell-surface receptors. Recent …
lipoprotein particles, cofactors for enzymes and ligands for cell-surface receptors. Recent …
Myeloperoxidase targets apolipoprotein AI, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions
B Shao, S Pennathur, JW Heinecke - Journal of Biological Chemistry, 2012 - ASBMB
Oxidative damage by myeloperoxidase (MPO) has been proposed to deprive HDL of its
cardioprotective effects. In vitro studies reveal that MPO chlorinates and nitrates specific …
cardioprotective effects. In vitro studies reveal that MPO chlorinates and nitrates specific …
Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein
Accumulation of low-density lipoprotein (LDL)-derived cholesterol by artery wall
macrophages triggers atherosclerosis, the leading cause of cardiovascular disease …
macrophages triggers atherosclerosis, the leading cause of cardiovascular disease …
Tyrosine 192 in apolipoprotein AI is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent …
High density lipoprotein (HDL) isolated from human atherosclerotic lesions and the blood of
patients with established coronary artery disease contains elevated levels of 3-nitrotyrosine …
patients with established coronary artery disease contains elevated levels of 3-nitrotyrosine …
The structure of apolipoprotein AI in high density lipoproteins
WS Davidson, TB Thompson - Journal of Biological Chemistry, 2007 - ASBMB
Not long ago, high density lipoproteins (HDL) 2 were second class citizens with regard to
therapeutic strategies for lowering the risk of atherosclerosis and coronary artery disease …
therapeutic strategies for lowering the risk of atherosclerosis and coronary artery disease …
Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein AI
High density lipoprotein (HDL) isolated from human atherosclerotic lesions and the blood of
patients with established coronary artery disease contains elevated levels of 3 …
patients with established coronary artery disease contains elevated levels of 3 …