[PDF][PDF] Extrahepatic replication of HCV: insights into clinical manifestations and biological consequences

JT Blackard, N Kemmer, KE Sherman - Hepatology, 2006 - Wiley Online Library
An estimated 170 million persons are infected with the hepatitis C virus (HCV) worldwide.
While hepatocytes are the major site of infection, a broad clinical spectrum of extrahepatic …

Interferon alpha treatment and thyroid dysfunction

Y Tomer, JT Blackard, N Akeno - … and metabolism clinics of North America, 2007 - Elsevier
Interferon alpha (IFNα) is the cornerstone therapeutic agent for chronic hepatitis C virus
(HCV) infection. Prospective studies have shown that up to 15% of HCV patients receiving …

The etiology of autoimmune thyroid disease: a story of genes and environment

Y Tomer, A Huber - Journal of autoimmunity, 2009 - Elsevier
Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's
thyroiditis (HT) are prevalent autoimmune diseases, affecting up to 5% of the general …

Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection

S Caronia, K Taylor, L Pagliaro, C Carr, U Palazzo… - Hepatology, 1999 - journals.lww.com
Non-insulin-dependent diabetes mellitus (NIDDM) may be associated with chronic hepatitis
C virus (HCV) infection. This was studied further in two parts. First, 1,151 patients with HCV …

Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response

SJ Polyak, KSA Khabar, DM Paschal, HJ Ezelle… - Journal of …, 2001 - Am Soc Microbiol
Hepatitis C virus (HCV), a major cause of liver disease worldwide, is frequently resistant to
the antiviral alpha interferon (IFN). The HCV nonstructural 5A (NS5A) protein has been …

[PDF][PDF] Persistence of hepatitis C virus in patients successfully treated for chronic hepatitis C

M Radkowski, JF Gallegos‐Orozco, J Jablonska… - …, 2005 - Wiley Online Library
It is unclear whether the current antiviral treatment for chronic hepatitis C virus (HCV)
infection results in complete elimination of the virus, or whether small quantities of virus …

Posttransplant diabetes mellitus in liver transplant recipients: risk factors, temporal relationship with hepatitis C virus allograft hepatitis, and impact on mortality1

S Baid, AB Cosimi, ML Farrell, DA Schoenfeld… - …, 2001 - journals.lww.com
Background. Recent studies suggest an association between diabetes mellitus and hepatitis
C virus (HCV) infection. Our aim was to determine (1) the prevalence and determinants of …

Identification of unique hepatitis C virus quasispecies in the central nervous system and comparative analysis of internal translational efficiency of brain, liver, and …

DM Forton, P Karayiannis, N Mahmud… - Journal of …, 2004 - Am Soc Microbiol
Reports of cerebral dysfunction in chronic hepatitis C virus (HCV) infection have led to the
suggestion that HCV may infect the central nervous system (CNS). We used reverse …

[HTML][HTML] Post‐transplant diabetes mellitus and HCV seropositive status after renal transplantation: meta‐analysis of clinical studies

F Fabrizi, P Martin, V Dixit, S Bunnapradist… - American Journal of …, 2005 - Elsevier
Hepatitis C virus (HCV) infection has a detrimental role on patient and graft survival after
renal transplantation (RT). Some studies have also implicated HCV in the development of …

Pregnancy complications associated with hepatitis C: data from a 2003-2005 Washington state birth cohort

SA Pergam, CC Wang, CM Gardella… - American journal of …, 2008 - Elsevier
OBJECTIVE: The objective of the study was to determine the effect of hepatitis C virus (HCV)
on selected maternal and infant birth outcomes. STUDY DESIGN: This population-based …