LncRNA-mediated adipogenesis in different adipocytes

P Zhang, S Wu, Y He, X Li, Y Zhu, X Lin… - International Journal of …, 2022 - mdpi.com
Long-chain noncoding RNAs (lncRNAs) are RNAs that do not code for proteins, widely
present in eukaryotes. They regulate gene expression at multiple levels through different …

RNA binding proteins in senescence: a potential common linker for age-related diseases?

A Varesi, LIM Campagnoli, A Barbieri, L Rossi… - Ageing Research …, 2023 - Elsevier
Aging represents the major risk factor for the onset and/or progression of various disorders
including neurodegenerative diseases, metabolic disorders, and bone-related defects. As …

Rna M6a Methylation Regulates Glycolysis of Beige Fat and Contributes to Systemic Metabolic Homeostasis

Y Li, Y Zhang, T Zhang, X Ping, D Wang… - Advanced …, 2023 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) modification has been implicated in the progression of
obesity and metabolic diseases. However, its impact on beige fat biology is not well …

[HTML][HTML] LncRNA DGUOK-AS1 facilitates non-small cell lung cancer growth and metastasis through increasing TRPM7 stability via m6A modification

Y Feng, F Wu, Y Wu, Z Guo, X Ji - Translational Oncology, 2023 - Elsevier
Abstract Background N6-methyladenosine (m6A) modification plays key roles in tumor
progression. LncRNA deoxyguanosine kinase antisense RNA 1 (DGUOK-AS1) has been …

IGF2BP2 promotes lncRNA DANCR stability mediated glycolysis and affects the progression of FLT3-ITD+ acute myeloid leukemia

S Wu, C Chi, S Weng, W Zhou, Z Liu - Apoptosis, 2023 - Springer
Internal tandem duplication (ITD) is the most common type of FLT3 mutation (FLT3-ITD),
accounting for about 25% of AML patients. The expression of DANCR in FLT3-ITD AML had …

Knockdown of Circular RNAs Using LNA-Modified Antisense Oligonucleotides

MB Løvendorf, A Holm, A Petri, CA Thrue… - nucleic acid …, 2023 - liebertpub.com
Circular RNAs (circRNAs) constitute an abundant class of covalently closed noncoding RNA
molecules that are formed by backsplicing from eukaryotic protein-coding genes. Recent …

lncRNA Hnscr Regulates Lipid Metabolism by Mediating Adipocyte Lipolysis

YF Guo, JY Sun, Y Liu, ZY Liu, Y Huang, Y Xiao… - …, 2023 - academic.oup.com
Obesity is a process of fat accumulation due to the imbalance between energy intake and
consumption. Long noncoding RNA (lncRNA) Hnscr is crucial for metabolic regulation, but …

linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability

ME O'Reilly, S Ho, J Coronel, L Zhu, W Liu, C Xue… - Cell Reports, 2024 - cell.com
Adipose tissue remodeling and dysfunction, characterized by elevated inflammation and
insulin resistance, play a central role in obesity-related development of type 2 diabetes …

Research progress of non-coding RNAs regulation on intramuscular adipocytes in domestic animals

Y Gong, Z Lin, Y Wang, Y Liu - Gene, 2023 - Elsevier
Intramuscular fat (IMF) is the main determinant of the economic value of domestic animal
meat, and has a vital impact on the sensory quality characteristics, while the content of IMF is …

N6-methyladenosine RNA modification: an emerging molecule in type 2 diabetes metabolism

H Zhang, Y Gu, Q Gang, J Huang, Q Xiao… - Frontiers in …, 2023 - frontiersin.org
Type 2 diabetes (T2D) is a metabolic disease with an increasing rate of incidence
worldwide. Despite the considerable progress in the prevention and intervention, T2D and …