Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …

Asthma increases worldwide without any definite reason and patient numbers double every
10 years. Drugs used for asthma therapy relax the muscles and reduce inflammation, but …

This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

Asthma is an obstructive airway disease, with a heterogeneous and multifactorial
pathogenesis. Although generally considered to be a disease principally driven by chronic …

Asthmatic airways are inflamed and undergo remodelling. Inhaled corticosteroids and long-
acting β2-agonist combinations are more effective than inhaled corticosteroid monotherapy …

Lung inflammation may occur due to viral and bacterial infections, structural damage, or
inhalation of dangerous particles. These injuries may be quickly resolved by the immune …

Rationale: Matrix metalloproteinase-1 (MMP-1) and mast cells are present in the airways of
people with asthma. Objectives: To investigate whether MMP-1 could be activated by mast …

Inflammation, airway hyper-responsiveness and airway remodelling are well-established
hallmarks of asthma, but their inter-relationships remain elusive. In order to obtain a better …

Even today two bacterial lung infections, namely pneumonia and tuberculosis, are among
the 10 most frequent causes of death worldwide. These infections still lack effective …

A variety of pulmonary insults can prompt the need for life-saving mechanical ventilation;
however, misuse, prolonged use, or an excessive inflammatory response, can result in …