Misuse of RPKM or TPM normalization when comparing across samples and sequencing protocols

S Zhao, Z Ye, R Stanton - Rna, 2020 - rnajournal.cshlp.org
In recent years, RNA-sequencing (RNA-seq) has emerged as a powerful technology for
transcriptome profiling. For a given gene, the number of mapped reads is not only …

Wild relatives of maize, rice, cotton, and soybean: treasure troves for tolerance to biotic and abiotic stresses

J Mammadov, R Buyyarapu, SK Guttikonda… - Frontiers in plant …, 2018 - frontiersin.org
Global food demand is expected to nearly double by 2050 due to an increase in the world's
population. The Green Revolution has played a key role in the past century by increasing …

Genome editing in plants: an overview of tools and applications

VS Kamburova, EV Nikitina… - … Journal of Agronomy, 2017 - Wiley Online Library
The emergence of genome manipulation methods promises a real revolution in
biotechnology and genetic engineering. Targeted editing of the genomes of living organisms …

Allergic diseases: a comprehensive review on risk factors, immunological mechanisms, link with COVID-19, potential treatments, and role of allergen bioinformatics

FM Aldakheel - International Journal of Environmental Research and …, 2021 - mdpi.com
The prevalence of allergic diseases is regarded as one of the key challenges in health
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …

GSVA score reveals molecular signatures from transcriptomes for biomaterials comparison

MR Ferreira, GA Santos, CA Biagi… - … research Part A, 2021 - Wiley Online Library
Two in silico methodologies were implemented to reveal the molecular signatures of
inorganic hydroxyapatite and β‐TCP materials from a transcriptome database to compare …

The challenge of analyzing the sugarcane genome

PP Thirugnanasambandam, NV Hoang… - Frontiers in plant …, 2018 - frontiersin.org
Reference genome sequences have become key platforms for genetics and breeding of the
major crop species. Sugarcane is probably the largest crop produced in the world (in weight …

Genome editing in plants: advancing crop transformation and overview of tools

T Shah, T Andleeb, S Lateef, MA Noor - Plant Physiology and Biochemistry, 2018 - Elsevier
Genome manipulation technology is one of emerging field which brings real revolution in
genetic engineering and biotechnology. Targeted editing of genomes pave path to address …

[HTML][HTML] Bioinformatics Goes Viral: I. Databases, Phylogenetics and Phylodynamics Tools for Boosting Virus Research

F Vello, F Filippini, I Righetto - Viruses, 2024 - mdpi.com
Computer-aided analysis of proteins or nucleic acids seems like a matter of course
nowadays; however, the history of Bioinformatics and Computational Biology is quite recent …

Genome-wide analysis of potassium transport genes in Gossypium raimondii suggest a role of GrHAK/KUP/KT8, GrAKT2. 1 and GrAKT1. 1 in response to abiotic …

F Azeem, R Zameer, MAR Rashid, I Rasul… - Plant Physiology and …, 2022 - Elsevier
Potassium (K+) is an important macro-nutrient for plants, which comprises almost 10% of
plant's dry mass. It plays a crucial role in the growth of plants as well as other important …

Unclasping potentials of genomics and gene editing in chickpea to fight climate change and global hunger threat

C Singh, R Kumar, H Sehgal, S Bhati, T Singhal… - Frontiers in …, 2023 - frontiersin.org
Genomics and genome editing promise enormous opportunities for crop improvement and
elementary research. Precise modification in the specific targeted location of a genome has …