The relatively new discipline of pharmacovigilance (PV) aims to monitor the safety of drugs
throughout their evolution and is essential to discovering new drug risks. Due to their …

Clinical evaluation of drugs before approval is based on the experimental design of clinical
trial with randomization of drug exposure. Unfortunately, conclusions of clinical trials are …

Introduction: The use of potentially inappropriate medications (PIM) is an alarming social risk
factor in cardiovascular patients. PIM administration may result in iatrogenic disorders and …

Aim We assessed the hepatic safety of novel oral anticoagulants (NOACs) analyzing the
publicly available US‐FDA adverse event reporting system (FAERS). Methods We extracted …

Background Drug-related problems are an important healthcare safety concern in the
growing population of older people. Prescription of potentially inappropriate medication …

Resumen GALLI, Thamires B.; REIS, Wálleri C. y ANDRZEJEVSKI, Vânia M.. Potentially
inappropriate prescribing and the risk of adverse drug reactions in critically ill older adults …

Background Older adults are more prone to develop adverse drug reactions (ADRs) since
they exhibit numerous risk factors. The first aim was to analyse the number of spontaneous …

Background Atropinic drugs can increase the risk of falls, cognitive impairment, and mortality
in older patients; however, whether exposure to atropinic drugs is associated with frailty …

Criteria have been developed to identify potentially inappropriate medications that can
enhance adverse reactions, highly prevalent in older patient's therapy. This study aimed to …

OBJECTIVES Polypharmacy is common in older adults and associated with adverse drug
events (ADEs). Several methods have been described in studies to help correlate ADE …