Endometriosis, a common cause of pelvic pain and female infertility, depends on the growth
of vascularized endometrial tissue at ectopic sites. Endometrial fragments reach the …

Abstract Background Neuroendocrine tumors (NETs) are a form of cancer that differ from
other neoplasia in that they synthesize, store, and secrete peptides, eg, chromogranin A …

The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

Owing to the heterogeneity of neuroendocrine neoplasms (NENs), the availability of reliable
circulating markers is critical for improving diagnostics, prognostic stratification, follow-up …

Chromogranin A (CgA)—the index member of the chromogranin/secretogranin secretory
protein family—is ubiquitously distributed in endocrine, neuroendocrine, and immune cells …

An accurate tumor marker is a critical tool in tumor management because it establishes an
uncertain diagnosis, offers a basis for individual prognostication, signals response to …

Chromogranin A, despite a number of limitations, is still the most valuable marker of
neuroendocrine tumors (NETs). Granins belong to the family of acidic proteins that constitute …

Background. Neuroendocrine tumors (NETs) are characterized by having behavior and
prognosis that depend upon tumor histology, primary site, staging, and proliferative index …

It is increasingly clear that inflammatory diseases and cancers are influenced by cleavage
products of the pro-hormone chromogranin A (CgA), such as the 21-amino acids long …

Interleukin (IL)-1β and IL-18 play critical roles in the induction of chronic pain
hypersensitivity. Their inactive forms are activated by caspase-1. However, little is known …