Understanding the earliest immune responses following HIV infection is critical to inform
future vaccines and therapeutics. Here, we review recent prospective human studies in at …

Human Immunodeficiency Virus (HIV) has plagued human society for a long time since its
discovery, causing a large number of patients to suffer and costing hundreds of millions of …

Natural killer (NK) cells are effector and regulatory innate immune cells and play a critical
role in the first line of defense against various viral infections. Although previous reports …

Mass and fluorescence cytometry are quantitative single cell flow cytometry approaches that
are powerful tools for characterizing diverse tissues and cellular systems. Here mass …

Objective: To determine associations between circulating markers of immune activation,
immune cell senescence, and inflammation with HIV-associated abnormalities of pulmonary …

Aim Differential patterns of peripheral memory T cell subsets in nonalcoholic fatty liver
disease (NAFLD) were assessed using flow cytometry (FCM) to elucidate their association …

CD8+ T cells play a significant role in the control of HIV replication, yet the associated
qualitative and quantitative factors that determine the outcome of infection remain obscure …

HIV epitope-specific T cell responses are often comprised of clonotypic expansions with
distinct functional properties. In HIV+ individuals, we measured programmed death-1 (PD-1) …

After initiation of antiretroviral therapy (ART), HIV loads and frequencies of HIV epitope-
specific immune responses decrease. A diverse virus-specific T cell receptor (TCR) …

Objective CD8+ T cells lacking CD28 were originally reported to be a characteristic feature
of juvenile idiopathic arthritis (JIA), but the relevance of these unusual cells to this disease …