SELEX stands for systematic evolution of ligands by exponential enrichment. This method,
described primarily in 1990 [Ellington, AD, Szostak, JW, 1990. In vitro selection of RNA …

Aptamers are in vitro selected DNA or RNA molecules that are capable of binding a wide
range of nucleic and non-nucleic acid molecules with high affinity and specificity. They have …

Recent times have experienced more than ever the impact of viral infections in humans.
Viral infections are known to cause diseases not only in humans but also in plants and …

Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most
important factor in rapidly developing and epidemiologically dangerous diseases, such as …

Viral infections cause a host of fatal diseases and seriously affect every form of life from
bacteria to humans. Although most viral infections can receive appropriate treatment thereby …

Hepatitis C virus (HCV) is a common pathogen with an estimated 170 million people
infected worldwide in the year 2000. 1 The virus was unambiguously identified in 1989 as …

Currently, the development of effective diagnostic reagents as well as treatments against
Hepatitis C virus (HCV) remains a high priority. In this study, we have described the …

Current technologies for aptamer discovery typically leverage the systematic evolution of
ligands by exponential enrichment (SELEX) concept by recursively panning semi …

The development of reagents with high affinity and specificity to the antigens of hepatitis C
virus (HCV) is important for the early stage diagnosis of its infection. Aptamers are short …

The aptamer field witnessed steady growth during the past 28 years as evident from the
exponentially increasing number of related publications. The field is “coming of age”, but like …