Cognition in multiple sclerosis: State of the field and priorities for the future
JF Sumowski, R Benedict, C Enzinger, M Filippi… - Neurology, 2018 - AAN Enterprises
Cognitive decline is recognized as a prevalent and debilitating symptom of multiple sclerosis
(MS), especially deficits in episodic memory and processing speed. The field aims to (1) …
(MS), especially deficits in episodic memory and processing speed. The field aims to (1) …
Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis
MA Rocca, MP Amato, N De Stefano… - The Lancet …, 2015 - thelancet.com
In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …
underlie many of the clinical symptoms, especially cognitive impairment. This relation …
Multiple sclerosis and cognition: synaptic failure and network dysfunction
M Di Filippo, E Portaccio, A Mancini… - Nature Reviews …, 2018 - nature.com
Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …
(MS), with important implications for the everyday life of individuals with MS and for disease …
The pathogenesis of tuberculous meningitis
AG Davis, UK Rohlwink, A Proust… - Journal of leukocyte …, 2019 - academic.oup.com
Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …
Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging
The mechanisms underlying the pathogenesis of multiple sclerosis induce the changes that
underpin relapse-associated and progressive disability. Disease mechanisms can be …
underpin relapse-associated and progressive disability. Disease mechanisms can be …
Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis
G Mandolesi, A Gentile, A Musella… - Nature Reviews …, 2015 - nature.com
Multiple sclerosis (MS) has long been regarded as a chronic inflammatory disease of the
white matter that leads to demyelination and eventually to neurodegeneration. In the past …
white matter that leads to demyelination and eventually to neurodegeneration. In the past …
Reduced gamma-aminobutyric acid concentration is associated with physical disability in progressive multiple sclerosis
Neurodegeneration is thought to be the major cause of ongoing, irreversible disability in
progressive stages of multiple sclerosis. Gamma-aminobutyric acid is the principle inhibitory …
progressive stages of multiple sclerosis. Gamma-aminobutyric acid is the principle inhibitory …
[HTML][HTML] Thalamic injury and cognition in multiple sclerosis
M Amin, D Ontaneda - Frontiers in Neurology, 2021 - frontiersin.org
Multiple sclerosis (MS) produces demyelination and degeneration in both gray and white
matter. Both cortical and deep gray matter injury is observed during the course of MS …
matter. Both cortical and deep gray matter injury is observed during the course of MS …
Correspondence among gray matter atrophy and atlas-based neurotransmitter maps is clinically relevant in multiple sclerosis
In multiple sclerosis (MS), gray matter (GM) atrophy progresses in a non-random manner,
possibly in regions with a high distribution of specific neurotransmitters involved in several …
possibly in regions with a high distribution of specific neurotransmitters involved in several …
Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities
Research advances support the idea that excessive activation of the glutamatergic pathway
plays an important part in the pathophysiology of multiple sclerosis. Beyond the well …
plays an important part in the pathophysiology of multiple sclerosis. Beyond the well …