Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …
Antibiotic discovery and resistance: the chase and the race
K Iskandar, J Murugaiyan, D Hammoudi Halat… - Antibiotics, 2022 - mdpi.com
The history of antimicrobial resistance (AMR) evolution and the diversity of the
environmental resistome indicate that AMR is an ancient natural phenomenon. Acquired …
environmental resistome indicate that AMR is an ancient natural phenomenon. Acquired …
Nanobiotics against antimicrobial resistance: harnessing the power of nanoscale materials and technologies
Given the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of
“post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the …
“post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the …
Back to Nature: Medicinal plants as promising sources for antibacterial drugs in the post-antibiotic era
Undoubtedly, the advent of antibiotics in the 19th century had a substantial impact,
increasing human life expectancy. However, a multitude of scientific investigations now …
increasing human life expectancy. However, a multitude of scientific investigations now …
Design and synthesis of novel antimicrobial agents
Z Breijyeh, R Karaman - Antibiotics, 2023 - mdpi.com
The necessity for the discovery of innovative antimicrobials to treat life-threatening diseases
has increased as multidrug-resistant bacteria has spread. Due to antibiotics' availability over …
has increased as multidrug-resistant bacteria has spread. Due to antibiotics' availability over …
Antibiotic resistant bacteria: current situation and treatment options to accelerate the development of a new antimicrobial arsenal
A Tarín-Pelló, B Suay-García… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Antibiotic resistance is one of the biggest public health threats worldwide.
Currently, antibiotic-resistant bacteria kill 700,000 people every year. These data represent …
Currently, antibiotic-resistant bacteria kill 700,000 people every year. These data represent …
Wastewater treatment plants, an “escape gate” for ESCAPE pathogens
Antibiotics are an essential tool of modern medicine, contributing to significantly decreasing
mortality and morbidity rates from infectious diseases. However, persistent misuse of these …
mortality and morbidity rates from infectious diseases. However, persistent misuse of these …
Heavy-Metal Trojan Horse: Enterobactin-Directed Delivery of Platinum(IV) Prodrugs to Escherichia coli
C Guo, EM Nolan - Journal of the American Chemical Society, 2022 - ACS Publications
The global crisis of untreatable microbial infections necessitates the design of new
antibiotics. Drug repurposing is a promising strategy for expanding the antibiotic repertoire …
antibiotics. Drug repurposing is a promising strategy for expanding the antibiotic repertoire …
Antibiotic adjuvants: Synergistic tool to combat multi-drug resistant pathogens
The rise of multi-drug resistant (MDR) pathogens poses a significant challenge to the field of
infectious disease treatment. To overcome this problem, novel strategies are being explored …
infectious disease treatment. To overcome this problem, novel strategies are being explored …
Drug repurposing to overcome microbial resistance
J Jampilek - Drug Discovery Today, 2022 - Elsevier
Infections are a growing global threat, and the number of resistant species of microbial
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …