Lead, a systemic toxicant affecting virtually every organ system, primarily affects the central
nervous system, particularly the developing brain. Consequently, children are at a greater …

Lead is a ubiquitous toxic heavy metal with unique physical and chemical properties that
make it suitable for a great variety of applications. Because of its high persistence in the …

Lead is an environmental toxicant that can induce oxidative stress (OS) via reactive oxygen
species (ROS) generation, which has been reported as an important mechanism underlying …

Background The impact of prenatal lead exposure on neurodevelopment remains unclear in
terms of consistency, the trimester of greatest vulnerability, and the best method for …

It is generally accepted that endocrine-disrupting chemicals (EDCs) play a role in a variety of
adverse health effects in an intact organism or its progeny as a consequence of changes in …

Oxidative stress is considered as a possible molecular mechanism involved in lead toxicity.
This study was carried out to investigate whether lead acetate could induce oxidative stress …

Abstract The human OGG1 (hOGG1) gene encodes a DNA glycosylase that is involved in
the excision repair of 8-hydroxy-2′-deoxyguanine (8-OH-dG) from oxidatively-damaged …

Lead is present in the natural and occupational environment and is reported to interact with
DNA, but the mechanism of this interaction is not fully understood. Using the alkaline comet …

Background Altered heart rate variability (HRV), a marker of poor cardiac autonomic
function, has been associated with sudden cardiac death and heart failure. Objective We …

Some of the adverse effects of lead (Pb) may be associated with oxidative damage of lipids,
proteins, or DNA. In a previous study a linkage was observed between the susceptibilities of …