Immune system acts as a host defensive mechanism protecting against attacking pathogens
and transformed cells, including cancer cells. Th17 cells are a specific subset of T helper …

T helper 17 (Th17) cells play critical roles in the pathogenesis of inflammatory and
autoimmune diseases, as well as in host protection against pathogens. The contribution of …

Combined with TCR stimuli, extracellular cytokine signals initiate the differentiation of naive
CD 4+ T cells into specialized effector T‐helper (Th) and regulatory T (Treg) cell subsets …

Primary vitreoretinal lymphoma (PVRL) is a rare malignancy that is speculated to arise
extraocularly, and preferentially invade and flourish in the ocular and CNS …

BACKGROUND Chronic inflammation has been associated with the development and
progression of human cancers including prostate cancer. The exact role of the inflammatory …

Despite the high cure rate of Hodgkin lymphoma (HL) with conventional radiochemotherapy,
HL is refractory in 15% to 30% of patients. 1 High-dose chemotherapy with autologous stem …

The relationships between immunological dysfunction, loss of tolerance and hematologic
malignancies have been a focus of attention in attempts to understand the appearance of a …

Background: CXCL13 and CXCR5 are a chemokine and receptor pair whose interaction is
critical for naïve B-cell trafficking and activation within germinal centers. We sought to …

Previous studies have indicated that cancer may be promoted and/or exacerbated by
inflammation and infection. The cytokines produced by activated innate immune cells that …

Research on T helper 17 (Th17) cells with regard to immunoediting has revealed elusive
results. Whereas enhanced Th17 response and related molecules such as interleukin (IL) …